Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 901799..902407 Replicon chromosome
Accession NZ_CP064908
Organism Synechococcus sp. CBW1107

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag I1E95_RS04865 Protein ID WP_197165942.1
Coordinates 902117..902407 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I1E95_RS04860 Protein ID WP_197165941.1
Coordinates 901799..902107 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1E95_RS04835 897267..897491 - 225 WP_197165937.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
I1E95_RS04840 897604..898011 + 408 WP_197165938.1 nucleotidyltransferase domain-containing protein -
I1E95_RS04845 897998..898298 + 301 Protein_956 hypothetical protein -
I1E95_RS04850 898711..899967 + 1257 WP_197161565.1 IS256 family transposase -
I1E95_RS04855 900136..901401 - 1266 WP_197165939.1 RNA-directed DNA polymerase -
I1E95_RS04860 901799..902107 - 309 WP_197165941.1 putative addiction module antidote protein Antitoxin
I1E95_RS04865 902117..902407 - 291 WP_197165942.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I1E95_RS04870 902538..903023 - 486 WP_197165943.1 hypothetical protein -
I1E95_RS04875 903456..904454 - 999 WP_197165944.1 DUF389 domain-containing protein -
I1E95_RS04880 905389..906360 - 972 WP_197165945.1 integron integrase -
I1E95_RS04885 906461..907192 + 732 WP_197165946.1 methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 901715..906360 4645


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10792.33 Da        Isoelectric Point: 10.6065

>T181877 WP_197165942.1 NZ_CP064908:c902407-902117 [Synechococcus sp. CBW1107]
MLEVRETTAYANWFRGLRDRAAKARIDIRVRRLSLGNPGDVRPVGEGVSELRIQFGPGYRIYFIQNGEEFILLLAGGDKS
SQAQDVKQAKSLARNL

Download         Length: 291 bp

>T181877 NZ_CP086195:c2959083-2958832 [Xanthomonas oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10639.01 Da        Isoelectric Point: 4.7778

>AT181877 WP_197165941.1 NZ_CP064908:c902107-901799 [Synechococcus sp. CBW1107]
MTKTFTTRWDPADHLVSSEDQAAYLEAALEDGDPKVIAAALGDIARAKGMTQIARDAGLGRESLYKALSAGGNPEFGTIL
KVISALGLQLHASPADEAKATV

Download         Length: 309 bp

>AT181877 NZ_CP086195:c2959388-2959110 [Xanthomonas oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References