Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 827708..828279 Replicon chromosome
Accession NZ_CP064908
Organism Synechococcus sp. CBW1107

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I1E95_RS04425 Protein ID WP_197165807.1
Coordinates 827923..828279 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A7T1MB51
Locus tag I1E95_RS04420 Protein ID WP_037979383.1
Coordinates 827708..827926 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1E95_RS04385 823224..823418 - 195 WP_197165788.1 hypothetical protein -
I1E95_RS04390 823422..824471 - 1050 WP_197165790.1 hypothetical protein -
I1E95_RS04395 824484..825161 - 678 WP_197165792.1 hypothetical protein -
I1E95_RS04400 825202..825444 - 243 WP_197165794.1 hypothetical protein -
I1E95_RS04405 825525..826217 - 693 WP_197165795.1 hypothetical protein -
I1E95_RS04410 826228..826662 - 435 WP_197165797.1 hypothetical protein -
I1E95_RS04415 826696..827637 - 942 WP_197165799.1 hypothetical protein -
I1E95_RS04420 827708..827926 + 219 WP_037979383.1 DUF433 domain-containing protein Antitoxin
I1E95_RS04425 827923..828279 + 357 WP_197165807.1 DUF5615 family PIN-like protein Toxin
I1E95_RS04430 828401..829564 - 1164 WP_197165809.1 Fic family protein -
I1E95_RS04435 829850..830047 + 198 WP_197165811.1 hypothetical protein -
I1E95_RS04440 830144..830887 + 744 WP_197165813.1 L,D-transpeptidase -
I1E95_RS04445 830942..831208 + 267 WP_197165815.1 hypothetical protein -
I1E95_RS04450 831323..831658 + 336 WP_197165817.1 hypothetical protein -
I1E95_RS04455 831932..832150 + 219 WP_197166716.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-79)

Antitoxin

Protein of unknown function DUF433

(6-61)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13128.11 Da        Isoelectric Point: 4.4692

>T181875 WP_197165807.1 NZ_CP064908:827923-828279 [Synechococcus sp. CBW1107]
MRLWLDAQLPPALALWIGAQPWGVDAVPVREIGLRDASDPEIFRQARAAEAVVMTKDRDFIRLLDEQSPPPQVIWLRLGN
SSNAALQQVLSTTLLPALELLRTGEPWVEIRPQANAEA

Download         Length: 357 bp

>T181875 NZ_CP086195:545234-545368 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 7904.99 Da        Isoelectric Point: 4.5006

>AT181875 WP_037979383.1 NZ_CP064908:827708-827926 [Synechococcus sp. CBW1107]
MAPSRITHNPEQCGGKPCIRGMRIRVRDVLELYAAGLSSEQILADYPDLEPEDLSAALDYAAREIDHPVLVG

Download         Length: 219 bp

>AT181875 NZ_CP086195:545018-545170 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7T1MB51

References