Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-MazE |
| Location | 8299384..8300012 | Replicon | chromosome |
| Accession | NZ_CP064879 | ||
| Organism | Tolypothrix sp. PCC 7601 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | HG267_RS33605 | Protein ID | WP_263420001.1 |
| Coordinates | 8299384..8299689 (-) | Length | 102 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A0D6KDR9 |
| Locus tag | HG267_RS33610 | Protein ID | WP_045874043.1 |
| Coordinates | 8299785..8300012 (-) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HG267_RS33585 (HG267_33545) | 8294966..8296861 | - | 1896 | WP_045874040.1 | ATP-binding protein | - |
| HG267_RS33590 (HG267_33550) | 8297140..8298429 | - | 1290 | WP_045874041.1 | phosphoribosylamine--glycine ligase | - |
| HG267_RS33595 (HG267_33555) | 8298581..8298787 | + | 207 | WP_155539609.1 | hypothetical protein | - |
| HG267_RS33600 | 8298945..8299076 | - | 132 | WP_255325363.1 | hypothetical protein | - |
| HG267_RS33605 (HG267_33560) | 8299384..8299689 | - | 306 | WP_263420001.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| HG267_RS33610 (HG267_33565) | 8299785..8300012 | - | 228 | WP_045874043.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| HG267_RS33615 (HG267_33570) | 8300127..8300354 | - | 228 | WP_096621716.1 | hypothetical protein | - |
| HG267_RS33620 (HG267_33575) | 8300326..8300565 | - | 240 | WP_045874044.1 | hypothetical protein | - |
| HG267_RS33625 (HG267_33580) | 8300699..8300914 | - | 216 | WP_155539611.1 | hypothetical protein | - |
| HG267_RS33630 (HG267_33585) | 8301596..8301769 | + | 174 | WP_263420002.1 | hypothetical protein | - |
| HG267_RS33635 (HG267_33590) | 8302084..8304531 | - | 2448 | WP_045874048.1 | VIT domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11052.83 Da Isoelectric Point: 4.4797
>T181874 WP_263420001.1 NZ_CP064879:c8299689-8299384 [Tolypothrix sp. PCC 7601]
VGISSITVAELEYGVAKSQQQEKNRTALLQFLLPLEIVDFNPTAATIYGSIRSDLETRGIIIGAMDMLIAAHALSLGVIL
VTNNLREFSRIPALLLENWVD
VGISSITVAELEYGVAKSQQQEKNRTALLQFLLPLEIVDFNPTAATIYGSIRSDLETRGIIIGAMDMLIAAHALSLGVIL
VTNNLREFSRIPALLLENWVD
Download Length: 306 bp
>T181874 NZ_CP086195:545018-545170 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8471.55 Da Isoelectric Point: 4.1630
>AT181874 WP_045874043.1 NZ_CP064879:c8300012-8299785 [Tolypothrix sp. PCC 7601]
MNTAKLSTDGTHQVVILPEDFQLTGTEVYIKKIGNAIILIAKDNSWQSLIESLDNFSDDFMTTREQPLIDTRESL
MNTAKLSTDGTHQVVILPEDFQLTGTEVYIKKIGNAIILIAKDNSWQSLIESLDNFSDDFMTTREQPLIDTRESL
Download Length: 228 bp
>AT181874 NZ_CP086195:545234-545368 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|