Detailed information of TA system
Overview
TA module
| Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
| Location | 7696217..7697109 | Replicon | chromosome |
| Accession | NZ_CP064879 | ||
| Organism | Tolypothrix sp. PCC 7601 | ||
Toxin (Protein)
| Gene name | hepT | Uniprot ID | - |
| Locus tag | HG267_RS31175 | Protein ID | WP_052335210.1 |
| Coordinates | 7696666..7697109 (+) | Length | 148 a.a. |
Antitoxin (Protein)
| Gene name | mntA | Uniprot ID | A0A0D6KQU4 |
| Locus tag | HG267_RS31170 | Protein ID | WP_045870813.1 |
| Coordinates | 7696217..7696669 (+) | Length | 151 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HG267_RS31150 (HG267_31145) | 7692027..7694204 | + | 2178 | WP_045870809.1 | type I-D CRISPR-associated helicase Cas3' | - |
| HG267_RS31155 (HG267_31150) | 7694485..7694688 | + | 204 | WP_045870810.1 | hypothetical protein | - |
| HG267_RS31160 (HG267_31155) | 7694903..7695106 | + | 204 | WP_045870811.1 | DUF433 domain-containing protein | - |
| HG267_RS31165 (HG267_31160) | 7695139..7696158 | + | 1020 | WP_045870812.1 | PDDEXK nuclease domain-containing protein | - |
| HG267_RS31170 (HG267_31165) | 7696217..7696669 | + | 453 | WP_045870813.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
| HG267_RS31175 (HG267_31170) | 7696666..7697109 | + | 444 | WP_052335210.1 | DUF86 domain-containing protein | Toxin |
| HG267_RS31180 (HG267_31175) | 7697102..7700464 | + | 3363 | WP_045870814.1 | type I-D CRISPR-associated protein Cas10d/Csc3 | - |
| HG267_RS31185 (HG267_31180) | 7700534..7701544 | + | 1011 | WP_045870815.1 | type I-D CRISPR-associated protein Cas7/Csc2 | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 148 a.a. Molecular weight: 16906.12 Da Isoelectric Point: 4.4596
>T181873 WP_052335210.1 NZ_CP064879:7696666-7697109 [Tolypothrix sp. PCC 7601]
MKNIDTVIVTTRLEFIARYLDNLKRFEAITWDDYLNNIDNQLITERLLQLMAQAAIDINDHILSKLNPGNSNTNFEAFIE
LGNYGVITPELAKQLAPSSGLRNRLVHEYDDIDPQQVFRAISFALQQYPLYVRQVNSYLISLSEENG
MKNIDTVIVTTRLEFIARYLDNLKRFEAITWDDYLNNIDNQLITERLLQLMAQAAIDINDHILSKLNPGNSNTNFEAFIE
LGNYGVITPELAKQLAPSSGLRNRLVHEYDDIDPQQVFRAISFALQQYPLYVRQVNSYLISLSEENG
Download Length: 444 bp
>T181873 NZ_CP086194:c4611348-4611196 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
Antitoxin
Download Length: 151 a.a. Molecular weight: 17359.02 Da Isoelectric Point: 5.3217
>AT181873 WP_045870813.1 NZ_CP064879:7696217-7696669 [Tolypothrix sp. PCC 7601]
MQNHTPTITELQELALQLPEKIPYLKMLVLFGSRATGNANAKSDWDFAVLCDEEQREAYIKNNISGLFELPMLIGEVLKI
NSDKIDIVELNHCSELIAHFVARDGKVLYESEAEEFEKFKQKVLLSKSELKKIEHIKRQNIEQFLQRWGV
MQNHTPTITELQELALQLPEKIPYLKMLVLFGSRATGNANAKSDWDFAVLCDEEQREAYIKNNISGLFELPMLIGEVLKI
NSDKIDIVELNHCSELIAHFVARDGKVLYESEAEEFEKFKQKVLLSKSELKKIEHIKRQNIEQFLQRWGV
Download Length: 453 bp
>AT181873 NZ_CP086194:c4611132-4610998 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|