Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 19580..20189 Replicon chromosome
Accession NZ_CP064879
Organism Tolypothrix sp. PCC 7601

Toxin (Protein)


Gene name relE Uniprot ID A0A0D6KBC2
Locus tag HG267_RS00080 Protein ID WP_045874609.1
Coordinates 19580..19942 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D6KB47
Locus tag HG267_RS00085 Protein ID WP_045874651.1
Coordinates 19932..20189 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG267_RS00060 (HG267_00055) 14590..14901 + 312 WP_045874605.1 P-II family nitrogen regulator -
HG267_RS00065 (HG267_00060) 14898..15599 + 702 WP_045874606.1 carbonic anhydrase -
HG267_RS00070 (HG267_00065) 15682..16323 + 642 WP_045874607.1 Uma2 family endonuclease -
HG267_RS00075 (HG267_00070) 16433..19225 - 2793 WP_045874608.1 preprotein translocase subunit SecA -
HG267_RS00080 (HG267_00075) 19580..19942 - 363 WP_045874609.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HG267_RS00085 (HG267_00080) 19932..20189 - 258 WP_045874651.1 hypothetical protein Antitoxin
HG267_RS00090 (HG267_00085) 20314..20862 - 549 WP_096621648.1 diheme cytochrome c -
HG267_RS00095 (HG267_00090) 21004..24570 + 3567 WP_096621646.1 CHAT domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(36-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13806.48 Da        Isoelectric Point: 4.7613

>T181870 WP_045874609.1 NZ_CP064879:c19942-19580 [Tolypothrix sp. PCC 7601]
MQSDNTVSIRFADEFEEKLYRLSKRFRNIRSDVQPIIEQLQQGNIVGDRISGLGEEYIVYKVRVRNSNIQKGKSGGYRLI
YQLESPTSILLLTIYSKSDQEDIAANEIRNILADFDSEEG

Download         Length: 363 bp

>T181870 NZ_CP086194:2159652-2159903 [Xanthomonas oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9527.83 Da        Isoelectric Point: 4.4169

>AT181870 WP_045874651.1 NZ_CP064879:c20189-19932 [Tolypothrix sp. PCC 7601]
MKAIEVTGKIDAQGNLILDEPIHGTTYPHQVRVIVLVPEPAETEELDPDDTPVEEIKASLRRALKQAKMGQTRPISELWD
RIDAE

Download         Length: 258 bp

>AT181870 NZ_CP086194:2159347-2159625 [Xanthomonas oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6KBC2

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6KB47

References