Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 389911..390272 Replicon chromosome
Accession NZ_CP064871
Organism Xanthomonas oryzae pv. oryzicola strain YN01

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IYN96_RS01745 Protein ID WP_011257368.1
Coordinates 390138..390272 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IYN96_RS01740 Protein ID WP_011407410.1
Coordinates 389911..390063 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IYN96_RS01715 (IYN96_01705) 386253..386936 - 684 WP_014505034.1 dTMP kinase -
IYN96_RS01720 387416..387953 - 538 Protein_328 GTPase -
IYN96_RS01725 (IYN96_01720) 387950..388348 - 399 Protein_329 hypothetical protein -
IYN96_RS01730 388340..388558 - 219 Protein_330 hypothetical protein -
IYN96_RS01735 (IYN96_01725) 388880..389803 + 924 WP_014505030.1 arginase -
IYN96_RS01740 (IYN96_01730) 389911..390063 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IYN96_RS01745 (IYN96_01735) 390138..390272 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IYN96_RS01750 (IYN96_01740) 390515..390725 + 211 Protein_334 CsbD family protein -
IYN96_RS01755 (IYN96_01745) 390894..392183 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
IYN96_RS01760 (IYN96_01750) 392314..393258 + 945 WP_044749698.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T181855 WP_011257368.1 NZ_CP064871:390138-390272 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T181855 NZ_CP086189:c7523-7197 [Xanthomonas oryzae]
ATGATGCGGGGTGACTTTGTGACCATCGCCATGCAAGGCGACTTCGGAAAACCACGGCCCGCTCTAGTGATCCAGGCCGA
CCAGTTTGACGCACACACCACCGTGACGGTGCTGCCGGTGACAAGCACGCTCGTTGCTGCGCCGCTGCTGCGCATTACCG
TTCATCCAAGTACCGACAATGGTTTGCAGAAGCCGTCTCAGGTGATGGTGGACAAGGCCATGACCGTGAAGCGTGACAAG
GTAGGTCGAGCCTTTGGGCGCATAGACGCTGATGCGTTGGTGGTAATTGAGCGCTGCCTGGCCGTGTTCTTGGGCATCGC
TAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT181855 WP_011407410.1 NZ_CP064871:389911-390063 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT181855 NZ_CP086189:c7690-7520 [Xanthomonas oryzae]
ATGGCAGGTCTGCGTCCGGTGCAAATTTGGGTGCCAGACACACGGCGGCCTGACTTCGCCGAGGAATGCCGCCGTCAGTG
TCGTCTTGCTGCACAAGCGGACATGGCGGACACCGACATGCAGCGCTTCATGGATGAGGCGCTAGCAGACATGGATGGCT
GGACGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References