Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1675220..1675712 Replicon chromosome
Accession NZ_CP064858
Organism Vibrio europaeus strain 07/118 T2

Toxin (Protein)


Gene name relE Uniprot ID A0A178JEV0
Locus tag IXK98_RS16305 Protein ID WP_069666344.1
Coordinates 1675458..1675712 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A178JDY4
Locus tag IXK98_RS16300 Protein ID WP_069544518.1
Coordinates 1675220..1675468 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXK98_RS16270 1671732..1672265 - 534 WP_069666338.1 lipocalin family protein -
IXK98_RS16275 1672299..1672796 - 498 WP_171383809.1 GNAT family N-acetyltransferase -
IXK98_RS16280 1672865..1673293 - 429 WP_171801590.1 hypothetical protein -
IXK98_RS16285 1673436..1674053 - 618 WP_069666341.1 LysE family translocator -
IXK98_RS16290 1674201..1674536 - 336 WP_171801591.1 hypothetical protein -
IXK98_RS16295 1674825..1675136 - 312 WP_171801592.1 antibiotic biosynthesis monooxygenase -
IXK98_RS16300 1675220..1675468 + 249 WP_069544518.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IXK98_RS16305 1675458..1675712 + 255 WP_069666344.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXK98_RS16310 1675824..1676234 - 411 WP_171801593.1 hypothetical protein -
IXK98_RS16315 1676370..1676915 - 546 WP_171801594.1 GNAT family N-acetyltransferase -
IXK98_RS16320 1677033..1677398 - 366 WP_171801595.1 VOC family protein -
IXK98_RS16325 1677569..1677880 - 312 WP_171801596.1 hypothetical protein -
IXK98_RS16330 1677941..1678792 - 852 WP_171801597.1 IS3 family transposase -
IXK98_RS16335 1678876..1679097 - 222 Protein_1515 transposase -
IXK98_RS16340 1679297..1679677 - 381 WP_171801598.1 energy transducer TonB -
IXK98_RS16345 1680307..1680672 - 366 WP_171802383.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1672299..1703530 31231


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-71)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9761.54 Da        Isoelectric Point: 10.3924

>T181849 WP_069666344.1 NZ_CP064858:1675458-1675712 [Vibrio europaeus]
MTYKLDFKKSALKEWKKLIERLGNPHVPASKLSGADNMYKIKLCQSGYRLVYKVQDDVIIVTVLAVGKRERSDVYRKAMK
RLDD

Download         Length: 255 bp

>T181849 NZ_CP086185:2568255-2568389 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9049.34 Da        Isoelectric Point: 3.9610

>AT181849 WP_069544518.1 NZ_CP064858:1675220-1675468 [Vibrio europaeus]
MTTRILADVAASITELKANPMKVAASAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp

>AT181849 NZ_CP086185:2568039-2568191 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A178JEV0

Antitoxin

Source ID Structure
AlphaFold DB A0A178JDY4

References