Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2026084..2026355 Replicon chromosome
Accession NZ_CP064847
Organism Escherichia coli strain 20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2026214..2026317 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2026084..2026355 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IPT86_RS09815 2022639..2023301 - 663 WP_000944256.1 exodeoxyribonuclease X -
IPT86_RS09820 2023325..2023981 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
IPT86_RS09825 2024083..2024313 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IPT86_RS09830 2024452..2024826 + 375 WP_000168747.1 CopC domain-containing protein YobA -
IPT86_RS09835 2024830..2025702 + 873 WP_075861812.1 copper homeostasis membrane protein CopD -
IPT86_RS09840 2025715..2026056 + 342 WP_000976472.1 YebY family protein -
- 2026084..2026355 - 272 - - Antitoxin
- 2026214..2026317 + 104 - - Toxin
IPT86_RS09845 2026452..2027108 + 657 WP_000814509.1 protein-serine/threonine phosphatase -
IPT86_RS09850 2027109..2027300 - 192 WP_001296140.1 YebW family protein -
IPT86_RS09855 2027405..2027641 - 237 WP_001295499.1 DUF1480 family protein -
IPT86_RS09860 2027759..2029198 - 1440 WP_077902351.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T181822 NZ_CP064847:2026214-2026317 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT181822 NZ_CP064847:c2026355-2026084 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References