Detailed information of TA system TA181789

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 961592..962138
• Replicon: chromosome
• Accession: NZ_CP064826
• Organism: Morganella morganii subsp. morganii strain ZJD581

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IZ187_RS04400
• Protein ID: WP_205515763.1
• Coordinates: 961857..962138 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IZ187_RS04395
• Protein ID: WP_214222532.1
• Coordinates: 961592..961873 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IZ187_RS04390 (IZ187_04390)	956758..961392	+	4635	WP_214222533.1	hemagglutinin repeat-containing protein	-
IZ187_RS04395 (IZ187_04395)	961592..961873	+	282	WP_214222532.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
IZ187_RS04400 (IZ187_04400)	961857..962138	+	282	WP_205515763.1	type II toxin-antitoxin system YafQ family toxin	Toxin
IZ187_RS04405 (IZ187_04405)	962387..963871	+	1485	WP_205515764.1	C69 family dipeptidase	-
IZ187_RS04410 (IZ187_04410)	963963..964415	-	453	WP_072869559.1	NfeD family protein	-
IZ187_RS04415 (IZ187_04415)	964412..965350	-	939	WP_186849052.1	SPFH domain-containing protein	-
IZ187_RS04420 (IZ187_04420)	965406..966263	-	858	WP_015422944.1	co-chaperone YbbN	-
IZ187_RS04425 (IZ187_04425)	966323..967108	-	786	WP_214222531.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-87)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10967.84 Da
• Isoelectric Point: 9.4535

>T181789 WP_205515763.1 NZ_CP064826:961857-962138 [Morganella morganii subsp. morganii]
MARTIERSSQFKKDYKREIKGIYRIMLNDSLQNILNILVNDLPIPEKYADHPLKGNWRTFRDCHLYPDLILIYKKEGGCC
LKLARLGSHSEIF

Nucleotide

• Length: 282 bp

>T181789 NZ_CP086138:c86414-86028 [Bradyrhizobium barranii subsp. barranii]
ATGGTGATCGACTCATCCGCCATTTTGGCGATTTTTTTGAATGAACCGGAAGCCAGCGAATTCGAGCATCGCATTGCGGC
CGATCCTGTCCGGTTGATTTCGGCGGCGACGGTGTTGGAAACCGGAATAGGGATCGAATCAAGGTTGGGCGATGGGGGCG
GCGGCGAGCTTGATCTTTGGCTACACAAGGTTGGTGTCGAGATTGTTCCGGTCACGGCCGGGCATGCGGATCAGGCACGG
CGGGCGTGGCGGCGATATGGGAAAGGCCGGCATCCCGCCAAGCTGAACTTTGGCGATTGCTTTTCTTACGCTCTCGCCGC
CCTCACCGGAGAACCTCTGCTGTTCAAGGGCAGCGATTTCTCGCAGACCGACATCAAGGCGGCCTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10451.17 Da
• Isoelectric Point: 6.9806

>AT181789 WP_214222532.1 NZ_CP064826:961592-961873 [Morganella morganii subsp. morganii]
MSKVEYVRAKIDPKLKAEAIETLESMGLTVSDAIRMLMIQIVEQKAMPFSVKSTQYRHAARTWAAIKELECGKGKKFDSI
SDLMADLQDGKDD

Nucleotide

• Length: 282 bp

>AT181789 NZ_CP086138:c86668-86414 [Bradyrhizobium barranii subsp. barranii]
ATGGCGCTGAGCATCAAGGATCCCGAAACCGAAAAACTCGCGCGCACGCTAGCCGAGCGGACAGGGGAAACCATCACCGT
CGCGACCCGACGGGCGATCGAGGATAGGTTGCGACGGATCGGGGCCGACGCGACCAAGGCCGCGCTGATTGAGGATATGG
AAGCCATTCGGCGCCGCCTCGCTGCCCTCCCGGTCCTCGATCCACGCAGCATGGATGACATCCTCGGGTACGACGAAAAC
GGCTTGCCGGTCTGA