181738

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4541972..4542333 Replicon chromosome
Accession NZ_CP064794
Organism Xanthomonas oryzae pv. oryzicola strain HGA4

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IZG20_RS20580 Protein ID WP_011257368.1
Coordinates 4542199..4542333 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IZG20_RS20575 Protein ID WP_011407410.1
Coordinates 4541972..4542124 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IZG20_RS20550 4538313..4538996 - 684 WP_014505034.1 dTMP kinase -
IZG20_RS20555 4539476..4540014 - 539 Protein_3905 GTPase -
IZG20_RS20560 4540011..4540409 - 399 Protein_3906 hypothetical protein -
IZG20_RS20565 4540401..4540619 - 219 Protein_3907 hypothetical protein -
IZG20_RS20570 4540941..4541864 + 924 WP_014505030.1 arginase -
IZG20_RS20575 4541972..4542124 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IZG20_RS20580 4542199..4542333 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IZG20_RS20585 4542578..4542787 + 210 WP_011407411.1 CsbD family protein -
IZG20_RS20590 4542956..4544245 + 1290 WP_048482945.1 tryptophan--tRNA ligase -
IZG20_RS20595 4544376..4545320 + 945 WP_048482946.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T181738 WP_011257368.1 NZ_CP064794:4542199-4542333 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T181738 NZ_CP086118:881420-881818 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTTTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT181738 WP_011407410.1 NZ_CP064794:4541972-4542124 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT181738 NZ_CP086118:881193-881420 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGCAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References