Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | omega-epsilon-zeta/- |
| Location | 5302..6881 | Replicon | chromosome |
| Accession | NZ_CP064794 | ||
| Organism | Xanthomonas oryzae pv. oryzicola strain HGA4 | ||
Toxin (Protein)
| Gene name | avrRxo1 | Uniprot ID | Q6TKR8 |
| Locus tag | IZG20_RS00030 | Protein ID | WP_014504815.1 |
| Coordinates | 5302..6567 (+) | Length | 422 a.a. |
Antitoxin (Protein)
| Gene name | arc1 | Uniprot ID | Q6TKR9 |
| Locus tag | IZG20_RS00035 | Protein ID | WP_041183485.1 |
| Coordinates | 6585..6881 (+) | Length | 99 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IZG20_RS00010 | 957..1421 | + | 465 | WP_149621897.1 | hypothetical protein | - |
| IZG20_RS00015 | 1698..2655 | - | 958 | Protein_2 | IS30-like element IS1112a family transposase | - |
| IZG20_RS00020 | 2840..3427 | - | 588 | Protein_3 | IS5 family transposase | - |
| IZG20_RS00025 | 3546..4922 | + | 1377 | Protein_4 | IS5-like element ISXo4 family transposase | - |
| IZG20_RS00030 | 5302..6567 | + | 1266 | WP_014504815.1 | zeta toxin family type III secretion system effector XopAJ/AvrRxo1 | Toxin |
| IZG20_RS00035 | 6585..6881 | + | 297 | WP_041183485.1 | hypothetical protein | Antitoxin |
| IZG20_RS00040 | 7117..8019 | + | 903 | WP_048482995.1 | IS30 family transposase | - |
| IZG20_RS00045 | 8126..9504 | + | 1379 | Protein_8 | IS5 family transposase | - |
| IZG20_RS00050 | 9554..9904 | + | 351 | Protein_9 | transposase | - |
| IZG20_RS00055 | 10034..11075 | + | 1042 | WP_229690183.1 | IS3 family transposase | - |
| IZG20_RS00060 | 11284..11871 | + | 588 | WP_229690184.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 1698..11075 | 9377 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 422 a.a. Molecular weight: 45260.83 Da Isoelectric Point: 6.7037
>T181735 WP_014504815.1 NZ_CP064794:5302-6567 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLENNIADPERAAKTRA
ALEKYSGKSWSAALAAHSELI
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLENNIADPERAAKTRA
ALEKYSGKSWSAALAAHSELI
Download Length: 1266 bp
>T181735 NZ_CP086118:316725-317093 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAAGCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAAGCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA
Antitoxin
Download Length: 99 a.a. Molecular weight: 11364.89 Da Isoelectric Point: 4.9649
>AT181735 WP_041183485.1 NZ_CP064794:6585-6881 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERNDIYERMYYVEYPN
VMTLKEFAHIVETLFSWS
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERNDIYERMYYVEYPN
VMTLKEFAHIVETLFSWS
Download Length: 297 bp
>AT181735 NZ_CP086118:316507-316728 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGTGCGGTGACGGGGGGGCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGTGCGGTGACGGGGGGGCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|