181721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 1158443..1159262 Replicon chromosome
Accession NZ_CP064784
Organism Klebsiella sp. BDA134-6

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag IYV58_RS05345 Protein ID WP_004129235.1
Coordinates 1158443..1158700 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag IYV58_RS05350 Protein ID WP_142446300.1
Coordinates 1158711..1159262 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IYV58_RS05330 1154209..1154985 - 777 WP_142469810.1 Uxu operon transcriptional regulator -
IYV58_RS05335 1155123..1156598 - 1476 WP_142481789.1 fructuronate reductase -
IYV58_RS05340 1156675..1157859 - 1185 WP_004129234.1 mannonate dehydratase -
IYV58_RS05345 1158443..1158700 + 258 WP_004129235.1 YjhX family toxin Toxin
IYV58_RS05350 1158711..1159262 + 552 WP_142446300.1 N-acetyltransferase Antitoxin
IYV58_RS05355 1159280..1160908 + 1629 WP_087828274.1 SAM-dependent methyltransferase -
IYV58_RS05360 1161304..1162350 + 1047 WP_004129248.1 LacI family transcriptional regulator -
IYV58_RS05365 1162394..1162813 - 420 WP_049115076.1 RbsD/FucU family protein -
IYV58_RS05370 1162861..1163625 - 765 WP_049115075.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(25-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T181721 WP_004129235.1 NZ_CP064784:1158443-1158700 [Klebsiella sp. BDA134-6]
MNLSRQEQRTLHVLAKGGRIAHVRDTSGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T181721 NZ_CP086111:1858949-1859254 [Skermanella rosea]
ATGTCCAAGACCGAAACCCGTCCATGGGACATCGTAGACAGCCTCACCAACGAGGAGCGTATCGCTGCATACCTGGAAGC
TGTCCTGGAGGACGGCGATCCGGAACTTGTCGCGGCAGCGCTCGGCGATATCGCGCGGGCGAAAGGCATGACGGACATAG
CGCGCCGCACCGGGCTGGGGCGACAGAGTCTGTACAAGGCCCTGGCGCCGGGCGGCAATCCGGAATTCGCAACCGTGTTG
AAGGTGATCCGCTCGCTCGGATTGCGCCTCACCGTCACCGTGGACCCTGAAGGTCCAGGAACCTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20049.96 Da        Isoelectric Point: 7.5099

>AT181721 WP_142446300.1 NZ_CP064784:1158711-1159262 [Klebsiella sp. BDA134-6]
MTNHSFTFHVASEGDTDDILNVETRAFGYSKEARLVASLLNDESACPTLSLLARHNGKAVGHILFTRAMFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGALIRHGIEQLKAIGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQRLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT181721 NZ_CP086111:1858648-1858938 [Skermanella rosea]
TTGATTGAAATTCAGCAGACCGATCTATTCGCCGCATGGATCGAGTCAGTTCGTGACGATCGCGCCCGTCTGCGGGTCGA
GACGCGGATTCGGCGACTGCAACTTGGCAATCCCGGAGACGTCAATCCAGTCGGAGAAGGCGTGTCGGAAATGAGGATCG
ACTATGGGCCGGGCTACAGAGTGTATTTCACCTGCCGGGGCCGGACGGTGATAGTCCTCCTGGCCGGCGGAGACAAGCGT
ACCCAGGATCTGGATATCGCGGCGGCTATCCGTCTGGCCCGGGAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References