Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 1528212..1528908 Replicon chromosome
Accession NZ_CP064781
Organism Azospira restricta strain DSM 18626

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag IWH25_RS07535 Protein ID WP_203388699.1
Coordinates 1528212..1528589 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag IWH25_RS07540 Protein ID WP_203388700.1
Coordinates 1528573..1528908 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IWH25_RS07515 1525589..1526473 + 885 WP_203388695.1 hypothetical protein -
IWH25_RS07520 1526525..1527121 + 597 WP_203388696.1 hypothetical protein -
IWH25_RS07525 1527136..1527981 + 846 WP_203388697.1 restriction endonuclease -
IWH25_RS07530 1528012..1528188 + 177 WP_203388698.1 hypothetical protein -
IWH25_RS07535 1528212..1528589 + 378 WP_203388699.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IWH25_RS07540 1528573..1528908 + 336 WP_203388700.1 helix-turn-helix domain-containing protein Antitoxin
IWH25_RS07545 1529097..1529333 + 237 WP_203388701.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
IWH25_RS07550 1529344..1529748 + 405 WP_203388702.1 type II toxin-antitoxin system VapC family toxin -
IWH25_RS07555 1529766..1532102 + 2337 WP_203388703.1 penicillin-binding protein 1C -
IWH25_RS07560 1532161..1532988 + 828 WP_203388704.1 mechanosensitive ion channel family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(20-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(15-94)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14177.12 Da        Isoelectric Point: 8.8061

>T181718 WP_203388699.1 NZ_CP064781:1528212-1528589 [Azospira restricta]
VTASPRKERPLHWVGSTKRDLLDFPDDVIDEFGYSLGVVQLGGQPPAAKPWKGEGPGVFELVEDARGDTYRVAYTVRFAK
AIYVLHCFQKKSPSGIRTARTDVELIHERLKLARDDYEVRYGKEK

Download         Length: 378 bp

>T181718 NZ_CP086111:840615-840875 [Skermanella rosea]
GTGCAGATCCAGATACTCCCGAAAGCGGCGAAGGACCTCAAGGCGCTGGCGCCGCCGGACCGAGCCCGCGTCGTCTCCAA
AATCGAGCAGTACGCCGCCGACCCCGCTTCGCTGGTCAACAACGTCAAGGCATTGCAGGGGTCTGACCTGTTTCGCCTGC
GCGTAGGGGATTATCGGATCCTTTTCACCGTTAACGAAGACGGCACCGTGTCTGTCCTGCTGGTCCACCGCGTTCGACAC
CGGAGAGAAGCCTATGACTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12467.35 Da        Isoelectric Point: 9.9988

>AT181718 WP_203388700.1 NZ_CP064781:1528573-1528908 [Azospira restricta]
MARKNESVEVGSGNVFKDLGYADADERKLRTQLAMRLNDLLKERKLTQTAAAQIFGIPQPHVSELRNYKLSRFSSERLLH
FITLLDKDVEIVIRPKAANHEAGHVSVLVAA

Download         Length: 336 bp

>AT181718 NZ_CP086111:840868-841194 [Skermanella rosea]
ATGACTGAGACGCTCACCATTTCCCGCGCCGAGTACGACGCGCTCACCGAGCGGGTCGAGGACCTGGAAGATATCCTGGC
TGCGATGAACGCGCGCGGTGGTCAGCCGATGCCGCTGGAGTGGGCCGGGCGAATCATCAATGGGGAGAGCGCCATCCGGG
TCTGGCGCGAGTTCCGGGGGCTGTCGCTGCGGGCGCTCGCCGCCAAGTCGGGTGTGAGCGCGGGTTATCTGTCCGAGATC
GAGGCGGGCAAGAAGCCCGGGTCGGTGGAGGCCTACAAGGCGCTCGCAGAGGCCTTGGACACGTCCGTTGATTGGCTGGT
CCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References