Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 223913..224700 Replicon chromosome
Accession NZ_CP064781
Organism Azospira restricta strain DSM 18626

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag IWH25_RS01040 Protein ID WP_203387509.1
Coordinates 223913..224410 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag IWH25_RS01045 Protein ID WP_203387510.1
Coordinates 224407..224700 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IWH25_RS01020 219076..219717 - 642 WP_203387505.1 alpha/beta hydrolase -
IWH25_RS01025 219876..222155 - 2280 WP_203387506.1 nitric-oxide reductase large subunit -
IWH25_RS01030 222317..222760 - 444 WP_203387507.1 Rrf2 family transcriptional regulator -
IWH25_RS01035 222958..223848 + 891 WP_203387508.1 fructosamine kinase family protein -
IWH25_RS01040 223913..224410 - 498 WP_203387509.1 GNAT family N-acetyltransferase Toxin
IWH25_RS01045 224407..224700 - 294 WP_203387510.1 DUF1778 domain-containing protein Antitoxin
IWH25_RS01050 225041..226243 - 1203 WP_203387511.1 ammonium transporter -
IWH25_RS01055 226419..227633 - 1215 WP_203387512.1 murein transglycosylase A -
IWH25_RS01060 227686..228573 + 888 WP_203387513.1 ATP-binding protein -
IWH25_RS01065 228570..229529 + 960 WP_203387514.1 Nudix family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18228.99 Da        Isoelectric Point: 9.0072

>T181717 WP_203387509.1 NZ_CP064781:c224410-223913 [Azospira restricta]
VSLRGPEPLGAQHRLESFDCGQPTLNDWLLRHARQAQASGSAKTFVVADDDRVAGYFSLTVGQIDMLEVPERISKGMGQY
PVPVVILARLAVSTPDQGRGVGFGMLQDAIRRTLLIAEQAGIRAMLTHPINEEASSFYTRFGFIASPLRERQLLLLLKDA
RRWVA

Download         Length: 498 bp

>T181717 NZ_CP086108:c6291-5719 [Skermanella mucosa]
ATCTTGGCCGGCTTCACCGTTGTCTATGATGCCTGCGTTCTTTATCCTGCACCTTTACGGGACCTGCTGATCGAACTCGC
CGCTGCGAACTTGTTCCGCGCGAAGTGGACTGATGCGATCCATGATGAATGGATCAGGAACTTGCTTTCCAACCGGCCGG
ATTTGGGTATCGAACGGCTGCGCCGAACACGGGAACTGATGAATACGGCTGTGCTCGATTGCCTGGTCAAAGGTTATGAG
CATCTGACTCCCGCCGTTTCTCTGCCGGACGAGGATGACCGCCATGTCGTCGCAGCCGCCATACACTCCCGCGCTGACGC
TATCGTGACGTTCAACCTGAAGGATTTCCCGGCGAGCGAGCTATCCAGGCACGATCTCGAAGCGGTCCACCCGGATGAAT
TCATTCAGCATCTGTTCGAACTGGACGGAGCGGCCGTCGTCATAGCGGCGCAGAGATGTCATCGTAAGCTCAAGAATCCG
CCGAAATCCGCAGGGGAATATCTTGATACCCTTCTCCGACAGTCGTTGCCAAAAACCGTGGCTTCTCTTCGGCCCTTCTC
CGAGGTGATCTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10773.32 Da        Isoelectric Point: 6.9819

>AT181717 WP_203387510.1 NZ_CP064781:c224700-224407 [Azospira restricta]
MAAIASSPAARSARLGLRATPEQEAVLRRAAEVAHKSLTEFILDSACLAAERTLLDQRLFMVSGSQYQTLMELLERPEQT
NEGLRDLFSRKAPWDAK

Download         Length: 294 bp

>AT181717 NZ_CP086108:c6740-6291 [Skermanella mucosa]
ATGAACGCGCTGATCAGGAGGCCGGAGAGCGTCGTACCGACTGACGAGGATACCCGACTGGCGGCGGAATTGAGCCGCGT
TTTGGCGGCAAACGGCGAGAATGCAGCACTCCGGGTGCAATTGGACGATGGGCGGGCACTGACGCTGCCCATGGCTGCGA
CCCGGTTGCTGGAGCAAGTATTGACCGAAATGGCACACGGAAATGCCGTCACCCTGATACCCGTCCATGCGGAGCTGACC
ACACAGGAAGCGGCGGATTACCTGAATGTGTCGCGTCCATACCTGGTGCGTCTGCTTGAAGAGAACTTCATCCCGTTCCA
CAAAGTCGGGACCCATCGCAGGGTCAGGTTCCAGGACCTGAAGACCTTTAAGGAACAGGCCGATGCGAAGCGTCGGGATG
CCATGGGCGAGCTTGTGGCCCAGGCTCAGGAACTGGACCTGGGCTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References