Detailed information of TA system TA181714

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2923495..2924051
• Replicon: chromosome
• Accession: NZ_CP064780
• Organism: Xanthomonas oryzae pv. oryzae strain DY89031(J18)

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: IV492_RS13855
• Protein ID: WP_229001948.1
• Coordinates: 2923495..2923746 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: IV492_RS13860
• Protein ID: WP_011408759.1
• Coordinates: 2923773..2924051 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IV492_RS13815	2919265..2920356	+	1092	WP_041182166.1	ribonuclease D	-
IV492_RS13820	2920432..2920769	-	338	Protein_2644	ATP-dependent DNA ligase	-
IV492_RS13830	2921051..2921227	-	177	Protein_2645	DUF3606 domain-containing protein	-
IV492_RS13835	2921449..2921850	+	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
IV492_RS24130	2922281..2922409	-	129	WP_012444694.1	hypothetical protein	-
IV492_RS23815	2922378..2922497	-	120	Protein_2648	IS3 family transposase	-
IV492_RS13845	2922714..2922968	-	255	WP_223293127.1	hypothetical protein	-
IV492_RS13850	2923037..2923234	-	198	WP_004541336.1	hypothetical protein	-
IV492_RS13855	2923495..2923746	-	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IV492_RS13860	2923773..2924051	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
IV492_RS13870	2924247..2924591	-	345	WP_199285675.1	hypothetical protein	-
IV492_RS13880	2925497..2926681	-	1185	WP_011408397.1	IS256-like element IS1113 family transposase	-
IV492_RS13885	2926846..2927037	+	192	Protein_2655	transposase	-
IV492_RS13890	2927126..2928091	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
IV492_RS13895	2928241..2928798	+	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T181714 WP_229001948.1 NZ_CP064780:c2923746-2923495 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T181714 NZ_CP086106:4415726-4416154 [Skermanella mucosa]
ATGATCGTCGATACCTCCGCGGTCATCGCGATTCTCGAGCTTGAACCCGAGGCTGCCGACTTCGCGGGTCTCATCGCGAA
GGCCGATACCCCTTGGATCTCTGCGGTTGCCGTAGTCGAGGCTGGAATTCTGGCGGAAAGCCGACGTGGCCCGGCGGGTG
CCGATGAATTGGACAGGTTTCTCGTCCGGGCCAAGTTTCAAATCATACCGTTCGACCATGTCCAGGCTCGGATCGCACGT
CAGGCATTTCGCCGGTACGGCAAGGGCCGCCACCCGGCCAGCCTGAATTTCGGCGATTGCATCGCCTATTCCCTGTCAAA
GGCTTCCGGCAAGCCTCTTCTGTTCAAAGGCAATGATTTCGGCAAAACCGATGTCATCACCTGCTTACCCACGTCCCCGC
TCCCCGTACAAGACGAGCCTATCGCATAG

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT181714 WP_011408759.1 NZ_CP064780:c2924051-2923773 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT181714 NZ_CP086106:4415472-4415729 [Skermanella mucosa]
ATGCCTCTTGATATCAAGGACCCGGAAGCTGACCGCCTGGCCAGCGAGCTAGCGCGGCGGCGCGGAGTGAGCGTCGCCGA
AGCCGTGTTGGCGGCCCTTCGGGAGCAGATCAGGCGCGAAGACGAGAAGAGCAATTCGAGCGTCACTGCCGGAGAACTTC
TCGAAATCGCCAAACGATACAGCAGCCTTCCCATTCTGGACGACCGGCCGGAGGAGGAAATCCTTGGCTACGATCAGCAT
GGCCTCCCGCGACGATGA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2