Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 449541..449891 Replicon chromosome
Accession NZ_CP064780
Organism Xanthomonas oryzae pv. oryzae strain DY89031(J18)

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IV492_RS02105 Protein ID WP_011257368.1
Coordinates 449757..449891 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IV492_RS02100 Protein ID WP_011407410.1
Coordinates 449541..449693 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV492_RS02075 445812..446495 - 684 WP_011257363.1 dTMP kinase -
IV492_RS23480 446975..447517 - 543 Protein_401 GTPase -
IV492_RS02090 447514..447978 - 465 Protein_402 hypothetical protein -
IV492_RS23485 447970..448188 - 219 Protein_403 hypothetical protein -
IV492_RS02095 448510..449433 + 924 WP_011407409.1 arginase -
IV492_RS02100 449541..449693 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IV492_RS02105 449757..449891 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IV492_RS02110 450135..450344 + 210 WP_011407411.1 CsbD family protein -
IV492_RS02115 450513..451802 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IV492_RS02120 451933..452877 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T181712 WP_011257368.1 NZ_CP064780:449757-449891 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T181712 NZ_CP086106:c2486765-2486349 [Skermanella mucosa]
ATGCGCCGCTTCATGCTCGACACCAATGTGTGTATCCGGGTCCTGCGCGATCGGCCGGCCAGCGCCCGGACGCGTTTCAA
CGACGAGGCCGATGGCCTGTCCATTTCGGCGGTCACCCTGGGCGAACTGCTGCATGGCGCTGCCAAGTCGGACCGGCCGG
CTGACATGCGCCGTGAGGTCGAACGGCTGGCCGCCCGTCTCGAGGTGCTGCCGTTCGACGACGAGGCCGCTGCGCATTAC
GGCGACATCCGGGCCGACCTGAAGCGCCGCGGCATGGTGATTGGCTCGTACGACCTGATGATCGCCGGCCACGCCCGCAG
CCGAGGCCTCGTCGTGGTCACCGGAAACCTGCGCGAATTCAGACGCGTCGACGGGCTGCGCTGCGAGGATTGGCTGGACG
AGTCCCCGGGCAGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT181712 WP_011407410.1 NZ_CP064780:449541-449693 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT181712 NZ_CP086106:c2486989-2486765 [Skermanella mucosa]
ATGCAAGCCCGTACCACCCTGTTCCACTCGAACCGCAGCCAAGCCGTCCGACTCCCGAAAGACGTTTCGTTCCCGCCGGG
AGTGCGCGACGTCTTGATCCTGCGCGAAGGTCCCCGACGCATCATCATCCCGGCCGACAGTGTATGGGACGACTTTTTCG
ATTCCCCCGGCATCGGTTTCCCGGACCGCGACCAGCCCGCCGCCCAGGAGCGCGAAGCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References