Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995613..1995758 Replicon chromosome
Accession NZ_CP064768
Organism Klebsiella pneumoniae subsp. pneumoniae strain HS20R14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995649..1995751 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995613..1995758 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HS20R14_RS09580 1990743..1992803 + 2061 WP_004151449.1 oligopeptidase B -
HS20R14_RS09585 1992807..1993466 - 660 WP_020324964.1 exodeoxyribonuclease X -
HS20R14_RS09590 1993545..1993775 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HS20R14_RS09595 1993888..1994262 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HS20R14_RS09600 1994266..1995135 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HS20R14_RS09605 1995152..1995490 + 339 WP_002911404.1 YebY family protein -
- 1995613..1995758 - 146 - - Antitoxin
- 1995649..1995751 + 103 - - Toxin
HS20R14_RS09610 1996127..1996270 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HS20R14_RS09615 1996375..1997343 - 969 WP_004151446.1 VirK/YbjX family protein -
HS20R14_RS09620 1997500..1998153 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HS20R14_RS09625 1998150..1998341 - 192 WP_002911395.1 YebW family protein -
HS20R14_RS09630 1998439..1998678 - 240 WP_002911393.1 YebV family protein -
HS20R14_RS09635 1998794..2000227 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T181675 NZ_CP064768:1995649-1995751 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT181675 NZ_CP064768:c1995758-1995613 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References