Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1329695..1330229 Replicon chromosome
Accession NZ_CP064761
Organism Companilactobacillus futsaii strain Chongqingii CQ16Z1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IT773_RS06410 Protein ID WP_057814812.1
Coordinates 1329695..1329958 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IT773_RS06415 Protein ID WP_057814815.1
Coordinates 1329948..1330229 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT773_RS06380 1325418..1325681 + 264 WP_162256560.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
IT773_RS06385 1325684..1325947 + 264 WP_195701102.1 Txe/YoeB family addiction module toxin -
IT773_RS06390 1326372..1327403 + 1032 WP_149029777.1 IS30 family transposase -
IT773_RS06395 1327912..1328178 + 267 WP_195701103.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
IT773_RS06400 1328171..1328533 + 363 WP_195701104.1 type II toxin-antitoxin system PemK/MazF family toxin -
IT773_RS06405 1328825..1329638 + 814 Protein_1247 EamA family transporter -
IT773_RS06410 1329695..1329958 - 264 WP_057814812.1 Txe/YoeB family addiction module toxin Toxin
IT773_RS06415 1329948..1330229 - 282 WP_057814815.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IT773_RS06420 1330655..1330897 + 243 WP_057814817.1 ATP-binding cassette domain-containing protein -
IT773_RS06425 1330783..1331124 + 342 WP_083484623.1 hypothetical protein -
IT773_RS06430 1331634..1331834 + 201 WP_057814819.1 hypothetical protein -
IT773_RS06435 1331903..1332145 + 243 Protein_1253 capsid protein -
IT773_RS06440 1332178..1333362 - 1185 WP_195701105.1 amidohydrolase -
IT773_RS06445 1333542..1334039 + 498 WP_195702092.1 sugar O-acetyltransferase -
IT773_RS06450 1334036..1334389 - 354 WP_057814821.1 NAD(P)H-binding protein -
IT773_RS06455 1334410..1334571 - 162 WP_195701106.1 hypothetical protein -
IT773_RS06460 1334880..1335137 + 258 WP_195701107.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1318188..1500688 182500


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-76)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10561.32 Da        Isoelectric Point: 10.3195

>T181669 WP_057814812.1 NZ_CP064761:c1329958-1329695 [Companilactobacillus futsaii]
MKIDRVSFTIKALSDYQYWQKQDRKTLKILNRIINDIIRHPFTGIGKPEPLKYKLDNCWSRRINKSDRIVYTVTNDSIII
IQCRYHY

Download         Length: 264 bp

>T181669 NZ_CP086061:2853744-2854490 [Bacillus sp. BC1-43]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATCGTGGCCGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCCATTCGGAAAACTTGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGAACGGTATCTCATTGTCGCAGTCAGTTTTGCTTTGATTGATGCTTTT
ATCTTCTTAAGTGCATATGTCAAAAAACTGGCCGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCTTCTCTT
TGCCACTATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10846.17 Da        Isoelectric Point: 5.2170

>AT181669 WP_057814815.1 NZ_CP064761:c1330229-1329948 [Companilactobacillus futsaii]
MATTATNISEARKNLKKLTDDVVDYDDHVIITKPKNRNVVIMSEKEYQSWKETMYLLGTEANRKNLDESLEQLNRGNLKT
ISKEEWDKLSNEN

Download         Length: 282 bp

>AT181669 NZ_CP086061:2854490-2854660 [Bacillus sp. BC1-43]
ATGGAACGTGCGTTTCAAAACAGATGCGAGCCCAGAGCGGCGAAGCCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References