Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 524822..525491 Replicon chromosome
Accession NZ_CP064760
Organism Microbacterium schleiferi strain A32-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IT882_RS02565 Protein ID WP_195693041.1
Coordinates 524822..525226 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IT882_RS02570 Protein ID WP_195693042.1
Coordinates 525228..525491 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT882_RS02555 520930..521262 + 333 WP_195693039.1 hypothetical protein -
IT882_RS02560 521411..524695 + 3285 WP_195693040.1 DEAD/DEAH box helicase -
IT882_RS02565 524822..525226 - 405 WP_195693041.1 type II toxin-antitoxin system VapC family toxin Toxin
IT882_RS02570 525228..525491 - 264 WP_195693042.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IT882_RS02575 525641..526246 - 606 WP_195693043.1 low molecular weight phosphatase family protein -
IT882_RS02580 526289..527569 - 1281 WP_195693044.1 type II toxin-antitoxin system HipA family toxin -
IT882_RS02585 527566..527781 - 216 WP_195693045.1 helix-turn-helix domain-containing protein -
IT882_RS02590 527935..528777 - 843 WP_195693046.1 hypothetical protein -
IT882_RS02595 529196..529840 + 645 WP_195693047.1 CPBP family intramembrane metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-117)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14590.72 Da        Isoelectric Point: 4.3053

>T181664 WP_195693041.1 NZ_CP064760:c525226-524822 [Microbacterium schleiferi]
MAVYLDTSALVKLVVDEPESAALLDWLKEPGRMPVSSDLARTELLRATRRAAPSRMVRAREVLDSLVLLQLSTATFERAA
TLDPLSLRSMDAVHVASAVELGDDLDSFVTYDDRQAEALTVLGIPVMQPAAQPE

Download         Length: 405 bp

>T181664 NZ_CP086060:c3056772-3056089 [Paracidovorax citrulli]
ATCTTCAAACGCTCGCTCGCAGAAACTCCAGAGGGAGCAAAACTTACCTCGGCGCAGGTACACGCCGAGTCGTGCATCCT
CGCTGACCGGCTTGAAGACGAACTCCGATTGCAGAAGACCGCGAGCGGCGCGGCGATCAGCATGCTGGTCGATAAGCGAC
TGGCTGGAGCGCACGAAATCGACGCGTACATCAAGCTGGCTCAGGAGACCGGTCGCAAAATCGAGTTGTGCGATATTGAT
GCTCCACTCGAGCAGTCACTCATGGGCGTGCTGCAGCGCAAGCCCGAAGGTGACGCCCCCCGGCCACCCTACGTTGCGGT
TGCCAACGGATTCTCGGCGGTTCGCGGGCACCGGCTCGATGTCATCGACAAGTTTCTCTCGAACCCGACCTTGGGGAGCT
ATCATCTATTCGGCACTACCGGGAATGGCAGCAAGGCGATGGTTGCCAGCGTCGTCAACGGTGAACTGAGCATTCATGAC
CCTCAGTTATACGAGGCCATTACAGATCCCCAAGGTGCCCGGGCAGGCGATAGCGGCGATCAGATCATTGACGCTGCGCT
GATCGACCGGCTGACCAAAGGTATAGACGACCCAGCGCGAGCCATGGATGCCCGCACCGCATTGGAGCGGTACGCGGGCA
TGACGTGGTCGGACGCTCTGGCCGCCCATAGTTCACTGACTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9342.63 Da        Isoelectric Point: 9.1274

>AT181664 WP_195693042.1 NZ_CP064760:c525491-525228 [Microbacterium schleiferi]
MDEVGIRALKQNASSVVAAAAAGETLWITDRGRRVAQLSPISQSGLDRLITAGRARPPRRAIADLMPPAPGDPLSTELHA
LRDDERF

Download         Length: 264 bp

>AT181664 NZ_CP086060:c3056074-3055778 [Paracidovorax citrulli]
ATGACAGGCCTGAAAGGCGCAGATGCGCTCGACTTCCATAAGAAACTCAAGGAACGCAATGCTGCTTTACGCAATGCGGA
GTTGAACGCGGCGAAGGAACTGGCCGACAAAAATGGCAAGGAGCCTTTTGATCTAGTGAAACTGGAGAGGCTTTGCGATA
CCAGTCAAGCAGGCCGCCTTGTTGAAGGGACCGAACGGCAAGCCATGTACGAATACATGTACTACGTCGAGTACAAGAAT
GTTGGCACGTTGCAGGATTTCGCCCGGGTGGTGACAACACTCGCGTCCTGGTCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References