Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4024503..4025140 Replicon chromosome
Accession NZ_CP064707
Organism Bradyrhizobium sp. 131

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVA73_RS18530 Protein ID WP_247370343.1
Coordinates 4024503..4024898 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVA73_RS18535 Protein ID WP_085353162.1
Coordinates 4024898..4025140 (-) Length 81 a.a.

Genomic Context

IVA73_RS18510IVA73_RS18515IVA73_RS18520IVA73_RS18525IVA73_RS18565IVA73_RS18530IVA73_RS18535IVA73_RS18540IVA73_RS18545IVA73_RS18550IVA73_RS18555IVA73_RS18560
Location: 4020311..4021402 (1092 bp)
Type: Others
Protein ID: WP_247370419.1
Location: 4021536..4022282 (747 bp)
Type: Others
Protein ID: WP_018457980.1
Location: 4022530..4023132 (603 bp)
Type: Others
Protein ID: WP_247903399.1
Location: 4023352..4024389 (1038 bp)
Type: Others
Protein ID: WP_247370346.1
Location: 4028656..4028913 (258 bp)
Type: Others
Protein ID: WP_018457991.1
Location: 4024503..4024898 (396 bp)
Type: Toxin
Protein ID: WP_247370343.1
Location: 4024898..4025140 (243 bp)
Type: Antitoxin
Protein ID: WP_085353162.1
Location: 4025198..4026271 (1074 bp)
Type: Others
Protein ID: WP_247370340.1
Location: 4026414..4026878 (465 bp)
Type: Others
Protein ID: WP_247370337.1
Location: 4026875..4027300 (426 bp)
Type: Others
Protein ID: WP_247370334.1
Location: 4027309..4027872 (564 bp)
Type: Others
Protein ID: WP_018457989.1
Location: 4027914..4028408 (495 bp)
Type: Others
Protein ID: WP_247370332.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IVA73_RS18510 (IVA73_18280)4020311..4021402+1092WP_247370419.1patatin-like phospholipase family protein-
IVA73_RS18515 (IVA73_18285)4021536..4022282+747WP_018457980.1TetR/AcrR family transcriptional regulator-
IVA73_RS18520 (IVA73_18290)4022530..4023132+603WP_247903399.1PepSY domain-containing protein-
IVA73_RS18525 (IVA73_18295)4023352..4024389+1038WP_247370346.1aspartate-semialdehyde dehydrogenase-
IVA73_RS18530 (IVA73_18300)4024503..4024898-396WP_247370343.1type II toxin-antitoxin system VapC family toxinToxin
IVA73_RS18535 (IVA73_18305)4024898..4025140-243WP_085353162.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
IVA73_RS18540 (IVA73_18310)4025198..4026271-1074WP_247370340.1tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA-
IVA73_RS18545 (IVA73_18315)4026414..4026878-465WP_247370337.1peptidylprolyl isomerase-
IVA73_RS18550 (IVA73_18320)4026875..4027300-426WP_247370334.1hypothetical protein-
IVA73_RS18555 (IVA73_18325)4027309..4027872-564WP_018457989.1peptidylprolyl isomerase-
IVA73_RS18560 (IVA73_18330)4027914..4028408-495WP_247370332.1pantetheine-phosphate adenylyltransferase-
IVA73_RS18565 (IVA73_18335)4028656..4028913+258WP_018457991.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-87)

Antitoxin

Antitoxin VapB-like

(2-79)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 13999.34 Da        Isoelectric Point: 10.3997

>T181658 WP_247370343.1 NZ_CP064707:c4024898-4024503 [Bradyrhizobium sp. 131]
MVLDTSAIVATVTNEPDGQRYRKAMLDAASLSMSAVAILETKIVLSARFGASAVKFFDELLEIAGIVVVPFDADMAKGAF
EAFQRFGKGRGTSGAAQHRRLCGLRLAKARSQPLLFKGAHFAKTDILPALT

Download         Length: 396 bp

>T181658 NZ_CP086016:c5058763-5058176 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAATTCCTTCCCGCATTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8872.03 Da        Isoelectric Point: 4.8146

>AT181658 WP_085353162.1 NZ_CP064707:c4025140-4024898 [Bradyrhizobium sp. 131]
MNIRSAKVDELAQRLARLTGEDIETALERAIEERLSRVASPAVDRRAALTSFFERTAGLPVLDSRPADEILGYDRFGLPS

Download         Length: 243 bp

>AT181658 NZ_CP086016:c5058109-5057255 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCAGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCATGTGCACAGCAGCTTCGCCCTGGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTGGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAAATGGAGCAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCATGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGGCCCGCTGGCGCGAGACGATGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCTCGCGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCACTGGAGGAACTGGCGGCGGCGGTCAATCTATCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGGCAGCGCCGGCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGTTGGAGGTGGCTCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGACCTACGGCGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References