Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2077221..2077921 Replicon chromosome
Accession NZ_CP064707
Organism Bradyrhizobium sp. 131

Toxin (Protein)


Gene name vapC Uniprot ID A0A1X3E9Q3
Locus tag IVA73_RS09355 Protein ID WP_018454985.1
Coordinates 2077221..2077646 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVA73_RS09360 Protein ID WP_018454984.1
Coordinates 2077643..2077921 (-) Length 93 a.a.

Genomic Context

IVA73_RS09330IVA73_RS09335IVA73_RS09345IVA73_RS09350IVA73_RS09365IVA73_RS09370IVA73_RS09375IVA73_RS09380IVA73_RS09340IVA73_RS09355IVA73_RS09360
Location: 2073924..2074334 (411 bp)
Type: Others
Protein ID: WP_018454990.1
Location: 2074557..2074748 (192 bp)
Type: Others
Protein ID: WP_018454989.1
Location: 2075610..2076284 (675 bp)
Type: Others
Protein ID: WP_018454987.1
Location: 2076376..2077218 (843 bp)
Type: Others
Protein ID: WP_018454986.1
Location: 2078153..2079703 (1551 bp)
Type: Others
Protein ID: WP_085361305.1
Location: 2079700..2080839 (1140 bp)
Type: Others
Protein ID: WP_018454982.1
Location: 2080852..2081937 (1086 bp)
Type: Others
Protein ID: WP_018454981.1
Location: 2081937..2082839 (903 bp)
Type: Others
Protein ID: WP_018454980.1
Location: 2074979..2075455 (477 bp)
Type: Others
Protein ID: WP_026232853.1
Location: 2077221..2077646 (426 bp)
Type: Toxin
Protein ID: WP_018454985.1
Location: 2077643..2077921 (279 bp)
Type: Antitoxin
Protein ID: WP_018454984.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IVA73_RS09330 (IVA73_09210)2073924..2074334+411WP_018454990.1acyl-CoA thioesterase-
IVA73_RS09335 (IVA73_09215)2074557..2074748+192WP_018454989.1hypothetical protein-
IVA73_RS09340 (IVA73_09220)2074979..2075455-477WP_026232853.1nuclear transport factor 2 family protein-
IVA73_RS09345 (IVA73_09225)2075610..2076284+675WP_018454987.1HAD-IA family hydrolase-
IVA73_RS09350 (IVA73_09230)2076376..2077218+843WP_018454986.1DeoR/GlpR family DNA-binding transcription regulator-
IVA73_RS09355 (IVA73_09235)2077221..2077646-426WP_018454985.1type II toxin-antitoxin system VapC family toxinToxin
IVA73_RS09360 (IVA73_09240)2077643..2077921-279WP_018454984.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
IVA73_RS09365 (IVA73_09245)2078153..2079703+1551WP_085361305.1glycerol-3-phosphate dehydrogenase-
IVA73_RS09370 (IVA73_09250)2079700..2080839+1140WP_018454982.1ABC transporter ATP-binding protein-
IVA73_RS09375 (IVA73_09255)2080852..2081937+1086WP_018454981.1ABC transporter ATP-binding protein-
IVA73_RS09380 (IVA73_09260)2081937..2082839+903WP_018454980.1sugar ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-74)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15519.85 Da        Isoelectric Point: 5.8803

>T181657 WP_018454985.1 NZ_CP064707:c2077646-2077221 [Bradyrhizobium sp. 131]
VNLLLDTNVLSEVQRPAPSPKVLSWLDTIDEDRAFISAASIAELRRGIALLEDGRRRAALAAWLARDLPERFAGRTLPID
HAVAERWGDLMAQSRRSGLALSVMDGFFAATALANNLMLVTRNVKDFAVFGVPLLNPWDNP

Download         Length: 426 bp

>T181657 NZ_CP086016:c3280390-3279812 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCTCTGGCCTTCGAGGACCAAC
TGGGCGGCCTGGACCTCGGCAAGGTCTTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGTCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10060.30 Da        Isoelectric Point: 6.0741

>AT181657 WP_018454984.1 NZ_CP064707:c2077921-2077643 [Bradyrhizobium sp. 131]
MTEHTAPDSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRSGDLEL
ERVHDAPHDELP

Download         Length: 279 bp

>AT181657 NZ_CP086016:c3281032-3280478 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTTCCCTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCACGCTGGGAGTCCGGTACCCAGGCGCTGCTGGGGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGACACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACACCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTACGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1X3E9Q3

Antitoxin

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Source
ID
Structure
No matching records found

References