Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-Phd |
| Location | 2077221..2077921 | Replicon | chromosome |
| Accession | NZ_CP064707 | ||
| Organism | Bradyrhizobium sp. 131 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A1X3E9Q3 |
| Locus tag | IVA73_RS09355 | Protein ID | WP_018454985.1 |
| Coordinates | 2077221..2077646 (-) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | IVA73_RS09360 | Protein ID | WP_018454984.1 |
| Coordinates | 2077643..2077921 (-) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IVA73_RS09330 (IVA73_09210) | 2073924..2074334 | + | 411 | WP_018454990.1 | acyl-CoA thioesterase | - |
| IVA73_RS09335 (IVA73_09215) | 2074557..2074748 | + | 192 | WP_018454989.1 | hypothetical protein | - |
| IVA73_RS09340 (IVA73_09220) | 2074979..2075455 | - | 477 | WP_026232853.1 | nuclear transport factor 2 family protein | - |
| IVA73_RS09345 (IVA73_09225) | 2075610..2076284 | + | 675 | WP_018454987.1 | HAD-IA family hydrolase | - |
| IVA73_RS09350 (IVA73_09230) | 2076376..2077218 | + | 843 | WP_018454986.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| IVA73_RS09355 (IVA73_09235) | 2077221..2077646 | - | 426 | WP_018454985.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| IVA73_RS09360 (IVA73_09240) | 2077643..2077921 | - | 279 | WP_018454984.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| IVA73_RS09365 (IVA73_09245) | 2078153..2079703 | + | 1551 | WP_085361305.1 | glycerol-3-phosphate dehydrogenase | - |
| IVA73_RS09370 (IVA73_09250) | 2079700..2080839 | + | 1140 | WP_018454982.1 | ABC transporter ATP-binding protein | - |
| IVA73_RS09375 (IVA73_09255) | 2080852..2081937 | + | 1086 | WP_018454981.1 | ABC transporter ATP-binding protein | - |
| IVA73_RS09380 (IVA73_09260) | 2081937..2082839 | + | 903 | WP_018454980.1 | sugar ABC transporter permease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15519.85 Da Isoelectric Point: 5.8803
>T181657 WP_018454985.1 NZ_CP064707:c2077646-2077221 [Bradyrhizobium sp. 131]
VNLLLDTNVLSEVQRPAPSPKVLSWLDTIDEDRAFISAASIAELRRGIALLEDGRRRAALAAWLARDLPERFAGRTLPID
HAVAERWGDLMAQSRRSGLALSVMDGFFAATALANNLMLVTRNVKDFAVFGVPLLNPWDNP
VNLLLDTNVLSEVQRPAPSPKVLSWLDTIDEDRAFISAASIAELRRGIALLEDGRRRAALAAWLARDLPERFAGRTLPID
HAVAERWGDLMAQSRRSGLALSVMDGFFAATALANNLMLVTRNVKDFAVFGVPLLNPWDNP
Download Length: 426 bp
>T181657 NZ_CP086016:c3280390-3279812 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCTCTGGCCTTCGAGGACCAAC
TGGGCGGCCTGGACCTCGGCAAGGTCTTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGTCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCTCTGGCCTTCGAGGACCAAC
TGGGCGGCCTGGACCTCGGCAAGGTCTTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGTCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 10060.30 Da Isoelectric Point: 6.0741
>AT181657 WP_018454984.1 NZ_CP064707:c2077921-2077643 [Bradyrhizobium sp. 131]
MTEHTAPDSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRSGDLEL
ERVHDAPHDELP
MTEHTAPDSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRSGDLEL
ERVHDAPHDELP
Download Length: 279 bp
>AT181657 NZ_CP086016:c3281032-3280478 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTTCCCTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCACGCTGGGAGTCCGGTACCCAGGCGCTGCTGGGGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGACACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACACCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTACGCCTGGTGGAAACCCTCTGA
ATGACCGAGCCTCTTCCCTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCACGCTGGGAGTCCGGTACCCAGGCGCTGCTGGGGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCTTGCTGGCCTGTTCGCCGACACGCGCCGCGCAATTCGGCGT
GCCCCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACACCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTACGCCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|