Detailed information of TA system TA181652

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 5978433..5979963
• Replicon: chromosome
• Accession: NZ_CP064703
• Organism: Bradyrhizobium sp. 170

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: IVB05_RS27825
• Protein ID: WP_247779146.1
• Coordinates: 5978433..5979326 (-)
• Length: 298 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: IVB05_RS27830
• Protein ID: WP_247787001.1
• Coordinates: 5979319..5979963 (-)
• Length: 215 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVB05_RS27820 (IVB05_27670)	5975014..5978358	+	3345	WP_247779145.1	UvrD-helicase domain-containing protein	-
IVB05_RS27825 (IVB05_27675)	5978433..5979326	-	894	WP_247779146.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
IVB05_RS27830 (IVB05_27680)	5979319..5979963	-	645	WP_247787001.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
IVB05_RS27835 (IVB05_27685)	5980249..5981874	+	1626	WP_247779147.1	TIGR04141 family sporadically distributed protein	-
IVB05_RS27840 (IVB05_27690)	5982120..5982878	-	759	WP_247779148.1	hypothetical protein	-
IVB05_RS27845 (IVB05_27695)	5983433..5984200	+	768	WP_247779149.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (42-266)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (11-57)

Sequences

Toxin

Protein

• Length: 298 a.a.
• Molecular weight: 33664.75 Da
• Isoelectric Point: 7.9549

>T181652 WP_247779146.1 NZ_CP064703:c5979326-5978433 [Bradyrhizobium sp. 170]
MPKKPKPPIKNMGASVRARLLNLSKQRRQPFDLLLNNYVLERLLYRLSQTQYRDRFILKGAMLLTKWFEDPLRPTRDLDL
LGIGNDDQDEMVRIFQEVCGASYNDGVVFDSNSVKVDRIREETEYGGLRITATAKVDTAQVRVVIDIAFGDSVEPGLQEI
DLPVLLDFPAPNLRAYARETVIAEKFQAMVMLGRANSRMKDLYDIWVLSRNFEFKGDTLPRAIAATFARRKTEIPKEIPD
ALTTAFAEDPTKVAQWNSFIEDVAFQPGILADVINDLNKFLMPQASAAHAINKKNST

Nucleotide

• Length: 894 bp

>T181652 NZ_CP086016:1314684-1314983 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin

Protein

• Length: 215 a.a.
• Molecular weight: 23745.73 Da
• Isoelectric Point: 10.8609

>AT181652 WP_247787001.1 NZ_CP064703:c5979963-5979319 [Bradyrhizobium sp. 170]
MPSLSRTQQERALSLLKQQGMVRLSEFVEAGITATTVARMKDKGLVLQLSRGLYQLPDAPIDTHHTLAEAAKLVPKGVVC
LTSALAFHGLTDAIPSRVWIAIGAKDRRPRIETPPLQFVRFGEKVLTSGIKEHVIEGVRVRIYIPAKTVVDLFRYRRPAG
NRYQKSPGLNLALEGLREALRRRKASPAEIARYANEAGVWKVVQPYLEAMTANA

Nucleotide

• Length: 645 bp

>AT181652 NZ_CP086016:1314980-1315270 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
CTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCTCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCGACATTGAAAACCATGCTGGCA
GTAATGCGAGCTTTGGGCGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA