Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 321474..322995 Replicon plasmid p172_1
Accession NZ_CP064702
Organism Bradyrhizobium sp. 172

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag IVB07_RS40170 Protein ID WP_247767948.1
Coordinates 322111..322995 (+) Length 295 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag IVB07_RS40165 Protein ID WP_247767946.1
Coordinates 321474..322118 (+) Length 215 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB07_RS40150 (IVB07_39680) 317609..318094 + 486 WP_247767943.1 hypothetical protein -
IVB07_RS40155 (IVB07_39685) 318234..319802 + 1569 WP_247767944.1 hypothetical protein -
IVB07_RS40160 (IVB07_39690) 320326..321240 + 915 WP_247767945.1 DUF3800 domain-containing protein -
IVB07_RS40165 (IVB07_39695) 321474..322118 + 645 WP_247767946.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IVB07_RS40170 (IVB07_39700) 322111..322995 + 885 WP_247767948.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IVB07_RS40175 (IVB07_39705) 323399..324268 + 870 WP_247767949.1 hypothetical protein -
IVB07_RS40180 (IVB07_39710) 324386..324763 + 378 WP_247767951.1 hypothetical protein -
IVB07_RS40185 (IVB07_39715) 324785..325255 + 471 WP_247767952.1 hypothetical protein -
IVB07_RS40190 (IVB07_39720) 325311..325988 + 678 WP_247767954.1 hypothetical protein -
IVB07_RS40195 (IVB07_39725) 326453..326566 + 114 Protein_325 DUF3606 domain-containing protein -
IVB07_RS40200 (IVB07_39730) 326601..326867 - 267 WP_247767956.1 hypothetical protein -
IVB07_RS40205 (IVB07_39735) 327374..327895 + 522 WP_247300134.1 thermonuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..356376 356376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-57)


Sequences

Toxin        


Download         Length: 295 a.a.        Molecular weight: 32764.63 Da        Isoelectric Point: 6.5679

>T181650 WP_247767948.1 NZ_CP064702:322111-322995 [Bradyrhizobium sp. 172]
MANPPKNVAASVRARLLTLSRERNQPFDLLLTRYVLERLLYRLGSTDYRNRFVLKGAMLLATWVDNQFRPTRDIDLLGSG
NPDPDALLAIFKEIAAVDAADGVIFDPASFTVDRIRDENEYGGVRIKGNATVDNARVRVVIDIAFGDAIEPGVQETDLPV
LLDFPAPKLRSYPRETVIAEKFQAMVALGLANTRLKDFYDVWVLIRSYKFEGDTLARAIKATFARRKTEIPTALLDAFTP
TFTEDVGKKDQWAAFTKQVAVDPGPLTDAAKMLAEFLMPRAQEARALKDGEKAT

Download         Length: 885 bp

>T181650 NZ_CP086014:145566-146090 [Pseudomonas aeruginosa]
ATGAAAATCATCGGAGTGCAGGACCTCCCCTGCTACCGAATGCACACTCCCAAGTGGTCCGTTGCGCCTACATCTGGAGC
TGGAGCTGCAACCCAGGGTGGCCGGGTTAACCGAAAGGGGCTAGAGGCTCTATACCTCTCGCTTGAGTCGGCAACGGCCA
TTGCTGAGTTTCAGCAAGGAAGCGCATTCCTTCCACCAGGTCTGCTGGTCAGCTATTCCCTCAGTCTGGACCGAGTGATC
GACTTCACCGGCGGCTATGACGATACCTGGGCCCCGATCTGGCAAGACTTTTTCTGCGACTGGAGAAAGATTCGCTTCAA
CGACGGCGTTGAACCGCCGAGCTGGATTGTCGGGGATCTGGCTATCGAGGCTGACTGTGCTGGGATTCTGTTCGAGTCCG
TTGCGAACCCTGGAGGTCGGAACCTGGTGCTTTTCACCGATCAGTTGCCGGTGCATGGGAATATTGTGGTAAACGATCCT
CGCGGGGATCTCCCTACCGACCAGTCATCTTGGACGCGCCCGTAG

Antitoxin


Download         Length: 215 a.a.        Molecular weight: 23554.33 Da        Isoelectric Point: 10.5694

>AT181650 WP_247767946.1 NZ_CP064702:321474-322118 [Bradyrhizobium sp. 172]
MAKPSSTQQDRAIELLKERGIVRPSELATAGVTAATIARMKEKGLVVQLGRGLYQLPDAPIDTHHSLAEAAKRVPKGVVA
LTSALAFHDLTDTIPSMVWLAIGPKDRQPLPTNPPIQFVRFNPERLQEGVEIHTIEGCPVKIFSPAKTVVDLFRYRRSAG
TRYRHSTGLNLALEGLREVLRTRKAKPSEIADFARKAGVWKAMQPYIEAMTANG

Download         Length: 645 bp

>AT181650 NZ_CP086014:145174-145569 [Pseudomonas aeruginosa]
ATGGCCAGCAAAGCCGTATTAGAGCTTCGCCCCACCAACTTCGCGGGCTTGATGGACGCTCTCAAAGAGGTGAACCGTGT
GATGTTCTCTCCTGAGCGCTTCCTCAAGGTTTTTTCGATGGACCAGCAGACCTTGGCGCTCCGGGCCCATGTCCATCGCA
ACACCGTGCGCAACGCGCCTGAATCGGAAAAGGTCCAAGCCTACATTCGTGATTCAGTGAAGGTTCTGCGTGCAGTGACC
GACATGGGCACGGACGTGACGAATGCCATCTTCTGGTTTAAGAACGAGCCTCTTTCCACGTTCAACTACAAGACCGCGGA
GGAAGTGGTCAGCGAAGGAAAAACCGAGCAGCTGATCGCTTTCCTTCAATCCTGGGAAGCTGGTGCGCAAGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References