Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5972127..5972827 Replicon chromosome
Accession NZ_CP064698
Organism Bradyrhizobium sp. 183

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB16_RS29075 Protein ID WP_247807794.1
Coordinates 5972402..5972827 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB16_RS29070 Protein ID WP_247807793.1
Coordinates 5972127..5972405 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB16_RS29050 (IVB16_28745) 5967210..5968112 - 903 WP_247807792.1 sugar ABC transporter permease -
IVB16_RS29055 (IVB16_28750) 5968112..5969197 - 1086 WP_247363618.1 ABC transporter ATP-binding protein -
IVB16_RS29060 (IVB16_28755) 5969210..5970349 - 1140 WP_018454982.1 ABC transporter ATP-binding protein -
IVB16_RS29065 (IVB16_28760) 5970346..5971896 - 1551 WP_085361305.1 glycerol-3-phosphate dehydrogenase -
IVB16_RS29070 (IVB16_28765) 5972127..5972405 + 279 WP_247807793.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB16_RS29075 (IVB16_28770) 5972402..5972827 + 426 WP_247807794.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB16_RS29080 (IVB16_28775) 5972830..5973672 - 843 WP_018454986.1 DeoR/GlpR family DNA-binding transcription regulator -
IVB16_RS29085 (IVB16_28780) 5973764..5974438 - 675 WP_018454987.1 HAD-IA family hydrolase -
IVB16_RS29090 (IVB16_28785) 5974593..5975069 + 477 WP_026232853.1 nuclear transport factor 2 family protein -
IVB16_RS29095 (IVB16_28790) 5975300..5975491 - 192 WP_018454989.1 hypothetical protein -
IVB16_RS29100 (IVB16_28795) 5975714..5976124 - 411 WP_018454990.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-74)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15567.89 Da        Isoelectric Point: 5.8803

>T181648 WP_247807794.1 NZ_CP064698:5972402-5972827 [Bradyrhizobium sp. 183]
VNLLLDTNVLSEFQRPAPSPKVLSWLDTIDEDRAFISAASIAELRRGIALLEDGRRRAALAAWLARDLPERFAGRTLPID
HAVAERWGDLMAQSRRSGLALSVMDGFFAATALANNLMLVTRNVKDFAVFGVPLLNPWDNP

Download         Length: 426 bp

>T181648 NZ_CP086010:c4721020-4720610 [Pseudomonas aeruginosa]
ATGCTCAAGTTCATGCTCGACACCAACATCTGCATCTTCACCATCAAAAACCGTCCGCAAGAGGTGCGCGAGGCGTTCCT
GCGCCACCACGACCAGATGTGCATCAGCACCGTGACGCTGATGGAGCTGATCTACGGCGCAGAGAAGTCCTCGAACCCCT
CGCGCAATCTTGCAGACGTGGAAGGCTTCGCTGCTCGTCTGGAGGTGCTCAAGTACGACCAGGAAGCTGCCGCCCACACC
GGCCAGCTCCGCGCTGAACTGGCCCGCCTGGGCAAGCAAATCGGCCCCTATGACCAGATGATCGCCGGGCACGCCCGCTC
TCAGGGCCTGATCGTGGTCACCAATAACCGCCGCGAGTTCGACCGCGTACCCGGCTTGAGAGTTGAGGATTGGGTCACCC
CAATCGTATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10115.38 Da        Isoelectric Point: 6.4834

>AT181648 WP_247807793.1 NZ_CP064698:5972127-5972405 [Bradyrhizobium sp. 183]
MTEHTAPDSPARDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRSGDLEL
ERVHDAPHDELP

Download         Length: 279 bp

>AT181648 NZ_CP086010:c4721250-4721020 [Pseudomonas aeruginosa]
ATGGAACAAGGTTCTGTTTTTCAGAGCAATCGTAGCCAGGCCGTAAGACTGCCCAAGGCAGTCGCGCTTCCCGATGACGT
TAAGCGTGTGGATGTGGTCGCTGTGGGGCGCGCCAGAATCATCACGCCTGCCGGCGAGTCTTGGGATAGCTGGTTCGATG
GCGAGGGCGTTACTTCCGACTTTATGGCAGAGCGTGAACAGCCTGCCGATCAGGAGCGCGAGACTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References