Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5974438..5975138 Replicon chromosome
Accession NZ_CP064695
Organism Bradyrhizobium sp. 184

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB17_RS29080 Protein ID WP_247807794.1
Coordinates 5974713..5975138 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB17_RS29075 Protein ID WP_247807793.1
Coordinates 5974438..5974716 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB17_RS29055 (IVB17_28750) 5969521..5970423 - 903 WP_247807792.1 sugar ABC transporter permease -
IVB17_RS29060 (IVB17_28755) 5970423..5971508 - 1086 WP_247363618.1 ABC transporter ATP-binding protein -
IVB17_RS29065 (IVB17_28760) 5971521..5972660 - 1140 WP_018454982.1 ABC transporter ATP-binding protein -
IVB17_RS29070 (IVB17_28765) 5972657..5974207 - 1551 WP_085361305.1 glycerol-3-phosphate dehydrogenase -
IVB17_RS29075 (IVB17_28770) 5974438..5974716 + 279 WP_247807793.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB17_RS29080 (IVB17_28775) 5974713..5975138 + 426 WP_247807794.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB17_RS29085 (IVB17_28780) 5975141..5975983 - 843 WP_018454986.1 DeoR/GlpR family DNA-binding transcription regulator -
IVB17_RS29090 (IVB17_28785) 5976075..5976749 - 675 WP_018454987.1 HAD-IA family hydrolase -
IVB17_RS29095 (IVB17_28790) 5976904..5977380 + 477 WP_026232853.1 nuclear transport factor 2 family protein -
IVB17_RS29100 (IVB17_28795) 5977611..5977802 - 192 WP_018454989.1 hypothetical protein -
IVB17_RS29105 (IVB17_28800) 5978025..5978435 - 411 WP_018454990.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-74)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15567.89 Da        Isoelectric Point: 5.8803

>T181647 WP_247807794.1 NZ_CP064695:5974713-5975138 [Bradyrhizobium sp. 184]
VNLLLDTNVLSEFQRPAPSPKVLSWLDTIDEDRAFISAASIAELRRGIALLEDGRRRAALAAWLARDLPERFAGRTLPID
HAVAERWGDLMAQSRRSGLALSVMDGFFAATALANNLMLVTRNVKDFAVFGVPLLNPWDNP

Download         Length: 426 bp

>T181647 NZ_CP086010:c4643901-4643146 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGCTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGTGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10115.38 Da        Isoelectric Point: 6.4834

>AT181647 WP_247807793.1 NZ_CP064695:5974438-5974716 [Bradyrhizobium sp. 184]
MTEHTAPDSPARDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRSGDLEL
ERVHDAPHDELP

Download         Length: 279 bp

>AT181647 NZ_CP086010:c4644404-4644036 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCTTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References