Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3933512..3934149 Replicon chromosome
Accession NZ_CP064693
Organism Bradyrhizobium sp. 187

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB19_RS18790 Protein ID WP_247370343.1
Coordinates 3933512..3933907 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB19_RS18795 Protein ID WP_085353162.1
Coordinates 3933907..3934149 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB19_RS18770 (IVB19_18545) 3929320..3930411 + 1092 WP_247370419.1 patatin-like phospholipase family protein -
IVB19_RS18775 (IVB19_18550) 3930545..3931291 + 747 WP_018457980.1 TetR/AcrR family transcriptional regulator -
IVB19_RS18780 (IVB19_18555) 3931539..3932141 + 603 WP_247370350.1 PepSY domain-containing protein -
IVB19_RS18785 (IVB19_18560) 3932361..3933398 + 1038 WP_247370346.1 aspartate-semialdehyde dehydrogenase -
IVB19_RS18790 (IVB19_18565) 3933512..3933907 - 396 WP_247370343.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB19_RS18795 (IVB19_18570) 3933907..3934149 - 243 WP_085353162.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
IVB19_RS18800 (IVB19_18575) 3934207..3935280 - 1074 WP_247370340.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
IVB19_RS18805 (IVB19_18580) 3935423..3935887 - 465 WP_247370337.1 peptidylprolyl isomerase -
IVB19_RS18810 (IVB19_18585) 3935884..3936309 - 426 WP_247370334.1 hypothetical protein -
IVB19_RS18815 (IVB19_18590) 3936318..3936881 - 564 WP_018457989.1 peptidylprolyl isomerase -
IVB19_RS18820 (IVB19_18595) 3936923..3937417 - 495 WP_247370332.1 pantetheine-phosphate adenylyltransferase -
IVB19_RS18825 (IVB19_18600) 3937665..3937922 + 258 WP_018457991.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-87)

Antitoxin

Antitoxin VapB-like

(2-79)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 13999.34 Da        Isoelectric Point: 10.3997

>T181646 WP_247370343.1 NZ_CP064693:c3933907-3933512 [Bradyrhizobium sp. 187]
MVLDTSAIVATVTNEPDGQRYRKAMLDAASLSMSAVAILETKIVLSARFGASAVKFFDELLEIAGIVVVPFDADMAKGAF
EAFQRFGKGRGTSGAAQHRRLCGLRLAKARSQPLLFKGAHFAKTDILPALT

Download         Length: 396 bp

>T181646 NZ_CP086010:3662282-3662860 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8872.03 Da        Isoelectric Point: 4.8146

>AT181646 WP_085353162.1 NZ_CP064693:c3934149-3933907 [Bradyrhizobium sp. 187]
MNIRSAKVDELAQRLARLTGEDIETALERAIEERLSRVASPAVDRRAALTSFFERTAGLPVLDSRPADEILGYDRFGLPS

Download         Length: 243 bp

>AT181646 NZ_CP086010:3661639-3662193 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References