Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 5421418..5421956 Replicon chromosome
Accession NZ_CP064690
Organism Bradyrhizobium sp. 192

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IVB24_RS25090 Protein ID WP_094977521.1
Coordinates 5421418..5421684 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IVB24_RS25095 Protein ID WP_094977520.1
Coordinates 5421690..5421956 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB24_RS25075 (IVB24_24805) 5418582..5419022 + 441 WP_247769411.1 DUF983 domain-containing protein -
IVB24_RS25080 (IVB24_24810) 5419053..5419802 + 750 WP_247769412.1 NUDIX hydrolase -
IVB24_RS25085 (IVB24_24815) 5420086..5421414 + 1329 WP_247769413.1 LLM class flavin-dependent oxidoreductase -
IVB24_RS25090 (IVB24_24820) 5421418..5421684 - 267 WP_094977521.1 Txe/YoeB family addiction module toxin Toxin
IVB24_RS25095 (IVB24_24825) 5421690..5421956 - 267 WP_094977520.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IVB24_RS25100 (IVB24_24830) 5422198..5422365 + 168 WP_008139339.1 50S ribosomal protein L33 -
IVB24_RS25105 (IVB24_24835) 5422710..5423468 + 759 WP_247769414.1 DUF6064 family protein -
IVB24_RS25110 (IVB24_24840) 5423511..5423963 + 453 WP_247769415.1 hypothetical protein -
IVB24_RS25115 (IVB24_24845) 5424138..5425325 + 1188 WP_247769416.1 acetyl-CoA C-acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10662.24 Da        Isoelectric Point: 8.9066

>T181637 WP_094977521.1 NZ_CP064690:c5421684-5421418 [Bradyrhizobium sp. 192]
MLIAWTEIAWQDYLRWQQEDEKILSAINDLIKDIKRDPFKGIGKPEPLKHDLRGWWSRRITGEHRLVYRLQGKDDAQQLV
IAQCRYHY

Download         Length: 267 bp

>T181637 NZ_CP085987:4187639-4188166 [Salmonella enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCGGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9664.97 Da        Isoelectric Point: 4.8254

>AT181637 WP_094977520.1 NZ_CP064690:c5421956-5421690 [Bradyrhizobium sp. 192]
MAHVSYTELRGNLAAYMDQVCDDRAPLVVTRQNARSVVMLSEEEYEGLVETVHLLKSPANAARLLRSIKEADEGKLVAHE
LIEPGSTG

Download         Length: 267 bp

>AT181637 NZ_CP085987:4187352-4187642 [Salmonella enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACATACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTAAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References