Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 4778462..4779146 Replicon chromosome
Accession NZ_CP064689
Organism Bradyrhizobium sp. 200

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB30_RS23050 Protein ID WP_247829368.1
Coordinates 4778462..4778896 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB30_RS23055 Protein ID WP_247829369.1
Coordinates 4778904..4779146 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB30_RS23010 (IVB30_22820) 4773752..4774276 + 525 WP_247829361.1 hypothetical protein -
IVB30_RS23015 (IVB30_22825) 4774273..4774644 - 372 WP_247829362.1 ArsC family reductase -
IVB30_RS23020 (IVB30_22830) 4774759..4774917 + 159 WP_247829363.1 DUF5993 family protein -
IVB30_RS23025 (IVB30_22835) 4774925..4775473 + 549 WP_247829364.1 disulfide bond formation protein B -
IVB30_RS23030 (IVB30_22840) 4775480..4776184 - 705 WP_247829365.1 glutathione S-transferase N-terminal domain-containing protein -
IVB30_RS23035 (IVB30_22845) 4776263..4777135 + 873 WP_247829366.1 SDR family oxidoreductase -
IVB30_RS23040 (IVB30_22850) 4777156..4777791 + 636 WP_247829367.1 HAD hydrolase-like protein -
IVB30_RS23045 (IVB30_22855) 4777834..4778376 - 543 WP_247838289.1 RNA 2',3'-cyclic phosphodiesterase -
IVB30_RS23050 (IVB30_22860) 4778462..4778896 - 435 WP_247829368.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB30_RS23055 (IVB30_22865) 4778904..4779146 - 243 WP_247829369.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB30_RS23060 (IVB30_22870) 4779275..4780996 - 1722 WP_247829370.1 dihydroxy-acid dehydratase -
IVB30_RS23065 (IVB30_22875) 4781088..4781438 - 351 WP_247829371.1 Lin0512 family protein -
IVB30_RS23070 (IVB30_22880) 4781627..4782577 - 951 WP_247829372.1 5-dehydro-4-deoxyglucarate dehydratase -
IVB30_RS23075 (IVB30_22885) 4782673..4783563 - 891 WP_247829373.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15448.75 Da        Isoelectric Point: 6.6444

>T181633 WP_247829368.1 NZ_CP064689:c4778896-4778462 [Bradyrhizobium sp. 200]
VYLVDTNIISSAAPGRPAPSALVEWMDVHSASLFLSVVTVAEIEDGIAKLMREGATRKSADLASWLETVLHLYGQRILVF
DAPTARIAGGVADQARGRGHAPGFADIIIAATARRHELTILSRNVRHFEPLGVPVLDPFTTLPS

Download         Length: 435 bp

>T181633 NZ_CP085987:3079810-3080121 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8825.15 Da        Isoelectric Point: 9.9933

>AT181633 WP_247829369.1 NZ_CP064689:c4779146-4778904 [Bradyrhizobium sp. 200]
MKEIQLRDAKASLSAVVDEAMRGKPAVITRHGKRQAVVVSYEEWERLSHVPTFGRLLMAAPLVADDLPNRNSSGPRTADL

Download         Length: 243 bp

>AT181633 NZ_CP085987:3080118-3080564 [Salmonella enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References