Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4118411..4119030 Replicon chromosome
Accession NZ_CP064689
Organism Bradyrhizobium sp. 200

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB30_RS19800 Protein ID WP_247837404.1
Coordinates 4118638..4119030 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB30_RS19795 Protein ID WP_247837403.1
Coordinates 4118411..4118641 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB30_RS19780 (IVB30_19620) 4114017..4114847 + 831 WP_247837400.1 universal stress protein -
IVB30_RS19785 (IVB30_19625) 4115010..4115378 + 369 WP_247837401.1 hypothetical protein -
IVB30_RS19790 (IVB30_19630) 4115556..4118249 + 2694 WP_247837402.1 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase -
IVB30_RS19795 (IVB30_19635) 4118411..4118641 + 231 WP_247837403.1 hypothetical protein Antitoxin
IVB30_RS19800 (IVB30_19640) 4118638..4119030 + 393 WP_247837404.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB30_RS19805 (IVB30_19645) 4119271..4120440 + 1170 WP_247837405.1 site-specific integrase -
IVB30_RS19810 (IVB30_19650) 4120606..4120848 + 243 WP_247837406.1 AlpA family phage regulatory protein -
IVB30_RS19815 (IVB30_19655) 4120845..4121183 + 339 WP_247837407.1 hypothetical protein -
IVB30_RS19820 (IVB30_19660) 4121344..4121532 + 189 WP_247837408.1 hypothetical protein -
IVB30_RS19825 (IVB30_19665) 4121546..4121767 + 222 WP_247837409.1 hypothetical protein -
IVB30_RS19830 (IVB30_19670) 4121754..4123040 + 1287 WP_247837410.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Pae0151-like, PIN domain

(3-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14546.64 Da        Isoelectric Point: 5.5692

>T181632 WP_247837404.1 NZ_CP064689:4118638-4119030 [Bradyrhizobium sp. 200]
MIVVDASALLEALLRTPAARAVEERLFEPQQTLHAPHLLDIEVAQVIRRYAAKGEIDDERGRAALADLADFPFRRYPHDF
LLPRVWDLRNNLTAYDAVYVALAEALDAALLTRDQRLAAAAGHHARVELV

Download         Length: 393 bp

>T181632 NZ_CP085987:c3078577-3078266 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8697.08 Da        Isoelectric Point: 11.7880

>AT181632 WP_247837403.1 NZ_CP064689:4118411-4118641 [Bradyrhizobium sp. 200]
MTTMIQIRNVPDALHRRLKSRAALAGMSLSDYLLSEIRQVAERPTLDELRARLERRPGMTPSVSPVQAIRAERDRQ

Download         Length: 231 bp

>AT181632 NZ_CP085987:c3078265-3077975 [Salmonella enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAACCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAGC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References