Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3710448..3711072 Replicon chromosome
Accession NZ_CP064689
Organism Bradyrhizobium sp. 200

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB30_RS17775 Protein ID WP_247837007.1
Coordinates 3710448..3710852 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB30_RS17780 Protein ID WP_247837009.1
Coordinates 3710842..3711072 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB30_RS17760 (IVB30_17610) 3705984..3708035 + 2052 WP_247837001.1 DUF4238 domain-containing protein -
IVB30_RS17765 (IVB30_17615) 3708136..3708564 + 429 WP_247837003.1 hypothetical protein -
IVB30_RS17770 (IVB30_17620) 3708561..3709745 + 1185 WP_247837005.1 hypothetical protein -
IVB30_RS17775 (IVB30_17625) 3710448..3710852 - 405 WP_247837007.1 PIN domain-containing protein Toxin
IVB30_RS17780 (IVB30_17630) 3710842..3711072 - 231 WP_247837009.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
IVB30_RS17785 (IVB30_17635) 3712022..3712441 + 420 WP_247838231.1 YciI family protein -
IVB30_RS17790 (IVB30_17640) 3712521..3713057 + 537 WP_247837011.1 dihydrofolate reductase family protein -
IVB30_RS17795 (IVB30_17645) 3713119..3713778 - 660 WP_247837012.1 TetR/AcrR family transcriptional regulator -
IVB30_RS17800 (IVB30_17650) 3713930..3714940 + 1011 WP_256474394.1 acetylhydrolase -
IVB30_RS17805 (IVB30_17655) 3714970..3715785 + 816 WP_247837014.1 DUF3313 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14658.69 Da        Isoelectric Point: 5.1448

>T181631 WP_247837007.1 NZ_CP064689:c3710852-3710448 [Bradyrhizobium sp. 200]
MPGSFFDTNVLVYLASGDVTKADRAEATLAKGGSISVQVLNELANVARRKMQMSWDETHAFLNMLRGLLTVHPLTVETHE
TGLRLAERYGLSIYDSMIAASALDAGCDTLWSEDMQHGMKLDEGLRIANPFRGG

Download         Length: 405 bp

>T181631 NZ_CP085987:c2758186-2757695 [Salmonella enterica]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGGAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8788.11 Da        Isoelectric Point: 10.8838

>AT181631 WP_247837009.1 NZ_CP064689:c3711072-3710842 [Bradyrhizobium sp. 200]
MQVAKWGNSLAVRLPAVVVEALGLKEGDEIEIHVAERRQFSIARKPGRDEWLKRLRTFRGRLPADFKFDRDEANAR

Download         Length: 231 bp

>AT181631 NZ_CP085987:c2758476-2758183 [Salmonella enterica]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATCGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References