Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5798868..5799559 Replicon chromosome
Accession NZ_CP064688
Organism Bradyrhizobium sp. 40

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB40_RS27875 Protein ID WP_247816907.1
Coordinates 5799134..5799559 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB40_RS27870 Protein ID WP_247816906.1
Coordinates 5798868..5799137 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB40_RS27850 (IVB40_27640) 5793950..5794852 - 903 WP_007595151.1 sugar ABC transporter permease -
IVB40_RS27855 (IVB40_27645) 5794852..5795937 - 1086 WP_027568538.1 ABC transporter ATP-binding protein -
IVB40_RS27860 (IVB40_27650) 5795950..5797089 - 1140 WP_247291327.1 ABC transporter ATP-binding protein -
IVB40_RS27865 (IVB40_27655) 5797086..5798636 - 1551 WP_247816905.1 glycerol-3-phosphate dehydrogenase -
IVB40_RS27870 (IVB40_27660) 5798868..5799137 + 270 WP_247816906.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB40_RS27875 (IVB40_27665) 5799134..5799559 + 426 WP_247816907.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB40_RS27880 (IVB40_27670) 5799562..5800404 - 843 WP_247291332.1 DeoR/GlpR family DNA-binding transcription regulator -
IVB40_RS27885 (IVB40_27675) 5800496..5801170 - 675 WP_247816908.1 HAD-IA family hydrolase -
IVB40_RS27890 (IVB40_27680) 5801325..5801801 + 477 WP_247357061.1 nuclear transport factor 2 family protein -
IVB40_RS27895 (IVB40_27685) 5802165..5802560 + 396 WP_247816909.1 nuclear transport factor 2 family protein -
IVB40_RS27900 (IVB40_27690) 5802786..5802977 - 192 WP_007595173.1 hypothetical protein -
IVB40_RS27905 (IVB40_27695) 5803193..5803603 - 411 WP_027568529.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-76)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15459.66 Da        Isoelectric Point: 4.8728

>T181629 WP_247816907.1 NZ_CP064688:5799134-5799559 [Bradyrhizobium sp. 40]
VNLLLDTNVLSEVQRPAPSPKVLSWLDTIDEDRAFISVASIAELRRGIALLEDGRRRAALAAWLAHDLPERFAGRTLSID
HAVAERWGDLMAQSRRSGVALSVMDGFFAATALANNLMLVTHNVTDFAVFGVPLLNPWDDP

Download         Length: 426 bp

>T181629 NZ_CP085987:c2453932-2453645 [Salmonella enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGTTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCCCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9640.86 Da        Isoelectric Point: 6.7253

>AT181629 WP_247816906.1 NZ_CP064688:5798868-5799137 [Bradyrhizobium sp. 40]
MTGHSTAPDSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSAEEWARKTARKGTLAEFLLASPLRSADLE
LERVHDELP

Download         Length: 270 bp

>AT181629 NZ_CP085987:c2453658-2453356 [Salmonella enterica]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References