Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5798868..5799559 Replicon chromosome
Accession NZ_CP064688
Organism Bradyrhizobium sp. 40

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB40_RS27875 Protein ID WP_247816907.1
Coordinates 5799134..5799559 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB40_RS27870 Protein ID WP_247816906.1
Coordinates 5798868..5799137 (+) Length 90 a.a.

Genomic Context


IVB40_RS27870IVB40_RS27875IVB40_RS27890IVB40_RS27895IVB40_RS27850IVB40_RS27855IVB40_RS27860IVB40_RS27865IVB40_RS27880IVB40_RS27885IVB40_RS27900IVB40_RS27905
Location: 5798868..5799137 (270 bp)
Type: Antitoxin
Protein ID: WP_247816906.1
Location: 5799134..5799559 (426 bp)
Type: Toxin
Protein ID: WP_247816907.1
Location: 5801325..5801801 (477 bp)
Type: Others
Protein ID: WP_247357061.1
Location: 5802165..5802560 (396 bp)
Type: Others
Protein ID: WP_247816909.1
Location: 5793950..5794852 (903 bp)
Type: Others
Protein ID: WP_007595151.1
Location: 5794852..5795937 (1086 bp)
Type: Others
Protein ID: WP_027568538.1
Location: 5795950..5797089 (1140 bp)
Type: Others
Protein ID: WP_247291327.1
Location: 5797086..5798636 (1551 bp)
Type: Others
Protein ID: WP_247816905.1
Location: 5799562..5800404 (843 bp)
Type: Others
Protein ID: WP_247291332.1
Location: 5800496..5801170 (675 bp)
Type: Others
Protein ID: WP_247816908.1
Location: 5802786..5802977 (192 bp)
Type: Others
Protein ID: WP_007595173.1
Location: 5803193..5803603 (411 bp)
Type: Others
Protein ID: WP_027568529.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IVB40_RS27850 (IVB40_27640)5793950..5794852-903WP_007595151.1sugar ABC transporter permease-
IVB40_RS27855 (IVB40_27645)5794852..5795937-1086WP_027568538.1ABC transporter ATP-binding protein-
IVB40_RS27860 (IVB40_27650)5795950..5797089-1140WP_247291327.1ABC transporter ATP-binding protein-
IVB40_RS27865 (IVB40_27655)5797086..5798636-1551WP_247816905.1glycerol-3-phosphate dehydrogenase-
IVB40_RS27870 (IVB40_27660)5798868..5799137+270WP_247816906.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
IVB40_RS27875 (IVB40_27665)5799134..5799559+426WP_247816907.1type II toxin-antitoxin system VapC family toxinToxin
IVB40_RS27880 (IVB40_27670)5799562..5800404-843WP_247291332.1DeoR/GlpR family DNA-binding transcription regulator-
IVB40_RS27885 (IVB40_27675)5800496..5801170-675WP_247816908.1HAD-IA family hydrolase-
IVB40_RS27890 (IVB40_27680)5801325..5801801+477WP_247357061.1nuclear transport factor 2 family protein-
IVB40_RS27895 (IVB40_27685)5802165..5802560+396WP_247816909.1nuclear transport factor 2 family protein-
IVB40_RS27900 (IVB40_27690)5802786..5802977-192WP_007595173.1hypothetical protein-
IVB40_RS27905 (IVB40_27695)5803193..5803603-411WP_027568529.1acyl-CoA thioesterase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-122)

Antitoxin

(14-76)


Sequences


Toxin        


Download         Length: 142 a.a.        Molecular weight: 15459.66 Da        Isoelectric Point: 4.8728

>T181629 WP_247816907.1 NZ_CP064688:5799134-5799559 [Bradyrhizobium sp. 40]
VNLLLDTNVLSEVQRPAPSPKVLSWLDTIDEDRAFISVASIAELRRGIALLEDGRRRAALAAWLAHDLPERFAGRTLSID
HAVAERWGDLMAQSRRSGVALSVMDGFFAATALANNLMLVTHNVTDFAVFGVPLLNPWDDP

Download         Length: 426 bp

>T181629 NZ_CP085987:c2453932-2453645 [Salmonella enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGTTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCCCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9640.86 Da        Isoelectric Point: 6.7253

>AT181629 WP_247816906.1 NZ_CP064688:5798868-5799137 [Bradyrhizobium sp. 40]
MTGHSTAPDSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVIVSAEEWARKTARKGTLAEFLLASPLRSADLE
LERVHDELP

Download         Length: 270 bp

>AT181629 NZ_CP085987:c2453658-2453356 [Salmonella enterica]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References