181345

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4128214..4128730 Replicon chromosome
Accession NZ_CP064666
Organism Salmonella sp. SJTUF14154

Toxin (Protein)


Gene name relE Uniprot ID A0A3V5VNJ7
Locus tag IVP16_RS19890 Protein ID WP_000220577.1
Coordinates 4128214..4128498 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag IVP16_RS19895 Protein ID WP_000212724.1
Coordinates 4128488..4128730 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVP16_RS19875 4123330..4124982 + 1653 WP_000155050.1 alpha,alpha-phosphotrehalase -
IVP16_RS19880 4125391..4127529 + 2139 WP_023226981.1 anaerobic ribonucleoside-triphosphate reductase -
IVP16_RS19885 4127746..4128210 + 465 WP_001009173.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
IVP16_RS19890 4128214..4128498 - 285 WP_000220577.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IVP16_RS19895 4128488..4128730 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IVP16_RS19900 4128808..4130721 - 1914 WP_023226980.1 BglG family transcription antiterminator -
IVP16_RS19905 4130738..4131478 - 741 WP_000779254.1 KDGP aldolase family protein -
IVP16_RS19910 4131475..4132593 - 1119 WP_023137277.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
IVP16_RS19915 4132577..4133710 - 1134 WP_023226979.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10912.71 Da        Isoelectric Point: 9.8739

>T181345 WP_000220577.1 NZ_CP064666:c4128498-4128214 [Salmonella sp. SJTUF14154]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNDLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

>T181345 NZ_CP085821:1889042-1889197 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT181345 WP_000212724.1 NZ_CP064666:c4128730-4128488 [Salmonella sp. SJTUF14154]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp

>AT181345 NZ_CP085821:c1889030-1888972 [Salmonella enterica subsp. enterica serovar Enteritidis]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V5VNJ7

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References