Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 3425630..3426250 | Replicon | chromosome |
Accession | NZ_CP064663 | ||
Organism | Salmonella sp. SJTUF14170 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | V1H8E6 |
Locus tag | IVP17_RS16700 | Protein ID | WP_001280991.1 |
Coordinates | 3426032..3426250 (+) | Length | 73 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | V1H4V6 |
Locus tag | IVP17_RS16695 | Protein ID | WP_000344807.1 |
Coordinates | 3425630..3426004 (+) | Length | 125 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IVP17_RS16685 | 3420769..3421962 | + | 1194 | WP_001039202.1 | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | - |
IVP17_RS16690 | 3421985..3425134 | + | 3150 | WP_001132508.1 | multidrug efflux RND transporter permease subunit | - |
IVP17_RS16695 | 3425630..3426004 | + | 375 | WP_000344807.1 | Hha toxicity modulator TomB | Antitoxin |
IVP17_RS16700 | 3426032..3426250 | + | 219 | WP_001280991.1 | hemolysin expression modulator Hha | Toxin |
IVP17_RS16705 | 3426429..3426980 | + | 552 | WP_001278793.1 | maltose O-acetyltransferase | - |
IVP17_RS16710 | 3427098..3427568 | + | 471 | WP_000136181.1 | membrane protein | - |
IVP17_RS16715 | 3427624..3427764 | - | 141 | WP_001197749.1 | type B 50S ribosomal protein L36 | - |
IVP17_RS16720 | 3427770..3428030 | - | 261 | WP_000801415.1 | type B 50S ribosomal protein L31 | - |
IVP17_RS16725 | 3428255..3429805 | + | 1551 | WP_023210786.1 | EAL domain-containing protein | - |
IVP17_RS16735 | 3430036..3430425 | + | 390 | WP_000961285.1 | MGMT family protein | - |
IVP17_RS16740 | 3430458..3431027 | - | 570 | WP_000779802.1 | YbaY family lipoprotein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 73 a.a. Molecular weight: 8613.97 Da Isoelectric Point: 8.9008
>T181322 WP_001280991.1 NZ_CP064663:3426032-3426250 [Salmonella sp. SJTUF14170]
MSDKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
MSDKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
Download Length: 219 bp
>T181322 NZ_CP085819:4016905-4017008 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 125 a.a. Molecular weight: 14453.27 Da Isoelectric Point: 5.1444
>AT181322 WP_000344807.1 NZ_CP064663:3425630-3426004 [Salmonella sp. SJTUF14170]
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAVNLQLNELIEHIATFALNYKIKYNEDNKLIAQIDEYL
DDTFMLFSSYGINTQDLQKWRKSGNRLFRCFVNATRANPVSLSC
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAVNLQLNELIEHIATFALNYKIKYNEDNKLIAQIDEYL
DDTFMLFSSYGINTQDLQKWRKSGNRLFRCFVNATRANPVSLSC
Download Length: 375 bp
>AT181322 NZ_CP085819:c4017010-4016865 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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