Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 10608..11170 Replicon plasmid unnamed
Accession NZ_CP064380
Organism Vibrio furnissii strain PartQ-Vfurnissii-RM8376

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IUJ52_RS15365 Protein ID WP_038152854.1
Coordinates 10868..11170 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag IUJ52_RS15360 Protein ID WP_004729600.1
Coordinates 10608..10853 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ52_RS15335 (IUJ52_15320) 6322..7296 - 975 WP_050780295.1 recombinase RecT -
IUJ52_RS15340 (IUJ52_15325) 7472..7939 - 468 WP_004729597.1 hypothetical protein -
IUJ52_RS15345 (IUJ52_15330) 8190..8417 - 228 WP_038152853.1 hypothetical protein -
IUJ52_RS15350 (IUJ52_15335) 8647..9570 + 924 WP_004729598.1 IS5 family transposase -
IUJ52_RS15355 (IUJ52_15340) 9871..10407 - 537 Protein_13 recombinase family protein -
IUJ52_RS15360 (IUJ52_15345) 10608..10853 + 246 WP_004729600.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IUJ52_RS15365 (IUJ52_15350) 10868..11170 + 303 WP_038152854.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IUJ52_RS15370 (IUJ52_15355) 11167..11769 - 603 WP_004729602.1 recombinase family protein -
IUJ52_RS15375 (IUJ52_15360) 12379..13455 - 1077 WP_038152856.1 replication initiation protein -
IUJ52_RS15380 (IUJ52_15365) 14399..15121 + 723 WP_004729604.1 hypothetical protein -
IUJ52_RS15385 (IUJ52_15370) 15111..15860 + 750 WP_038152858.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..76098 76098
- flank IS/Tn - - 8647..9570 923


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-56)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11644.32 Da        Isoelectric Point: 6.7572

>T181033 WP_038152854.1 NZ_CP064380:10868-11170 [Vibrio furnissii]
MSSYKLSPLAQSDLTDIRRYTIEHWGSTQWSVYFNELQESMSLLASNELIGIQIPEMGERYYRFPLKHHVIYYITQEDHI
VIVAVLGKHMSPAKHFASIS

Download         Length: 303 bp

>T181033 NZ_CP085799:3905569-3905844 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9115.57 Da        Isoelectric Point: 4.5702

>AT181033 WP_004729600.1 NZ_CP064380:10608-10853 [Vibrio furnissii]
MQSLTANTAKTKFGDLLMKVQREPVQISKNGSPVAVMMSCEEYEQLEALKMMLVKSRFEQAEIDIRNGDLVDGDEFMKSL
A

Download         Length: 246 bp

>AT181033 NZ_CP085799:3905306-3905566 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCACGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References