Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1677877..1678418 Replicon chromosome
Accession NZ_CP064377
Organism Achromobacter xylosoxidans strain PartM-Axylosoxidans-RM8376

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IUJ48_RS07710 Protein ID WP_223203203.1
Coordinates 1678149..1678418 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IUJ48_RS07705 Protein ID WP_024069590.1
Coordinates 1677877..1678143 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ48_RS07685 (IUJ48_07655) 1673116..1673322 + 207 WP_006385007.1 oxidoreductase-like domain-containing protein -
IUJ48_RS07690 (IUJ48_07660) 1673375..1675801 - 2427 WP_070543066.1 TonB-dependent receptor -
IUJ48_RS07695 (IUJ48_07665) 1676061..1677110 - 1050 WP_024069592.1 FecR domain-containing protein -
IUJ48_RS07700 (IUJ48_07670) 1677103..1677630 - 528 WP_024069591.1 sigma-70 family RNA polymerase sigma factor -
IUJ48_RS07705 (IUJ48_07675) 1677877..1678143 + 267 WP_024069590.1 ribbon-helix-helix domain-containing protein Antitoxin
IUJ48_RS07710 (IUJ48_07680) 1678149..1678418 + 270 WP_223203203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IUJ48_RS07715 (IUJ48_07685) 1678424..1678861 - 438 WP_020928528.1 acetyltransferase -
IUJ48_RS07720 (IUJ48_07690) 1678874..1680613 - 1740 WP_024069589.1 hypothetical protein -
IUJ48_RS07725 (IUJ48_07695) 1680671..1681537 - 867 WP_024069588.1 ABC transporter permease -
IUJ48_RS07730 (IUJ48_07700) 1681543..1682466 - 924 WP_006385014.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10450.11 Da        Isoelectric Point: 10.7271

>T181027 WP_223203203.1 NZ_CP064377:1678149-1678418 [Achromobacter xylosoxidans]
MKWTSKALSDLARLHEFLAAVNRPAAVRAVQALVKASSVLPTNSRIGEQLFQFEPREVRRILVGEYEIRYEIRDSIIYVL
RLWHTRENR

Download         Length: 270 bp

>T181027 NZ_CP085799:c2907238-2906954 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGCAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGATCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGCTTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGTAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9699.04 Da        Isoelectric Point: 4.5720

>AT181027 WP_024069590.1 NZ_CP064377:1677877-1678143 [Achromobacter xylosoxidans]
MSPATKVLTAHVPLPLAEKVDQMAVRLDRSRGWIVKQALSAWIAQEEERDKLTEQALADVDAGRIVDDQAVQAWAESLGS
DQPLPLPR

Download         Length: 267 bp

>AT181027 NZ_CP085799:c2907470-2907228 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References