Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1712807..1713041 Replicon chromosome
Accession NZ_CP064376
Organism Shigella sonnei strain PartP-Ssonnei-RM8376

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1712808..1712911 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1712807..1713041 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ51_RS08915 1709090..1709410 + 321 WP_241556168.1 exodeoxyribonuclease VIII -
IUJ51_RS08920 1709388..1709504 + 117 Protein_1740 host-nuclease inhibitor Gam family protein -
IUJ51_RS08925 1709567..1710723 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -
IUJ51_RS08930 1710866..1711563 + 698 WP_094096600.1 IS1-like element IS1A family transposase -
IUJ51_RS08935 1711600..1712676 + 1077 WP_140046268.1 phage integrase Arm DNA-binding domain-containing protein -
- 1712807..1713041 + 235 - - Antitoxin
- 1712808..1712911 - 104 - - Toxin
IUJ51_RS08940 1713069..1713410 - 342 WP_000976476.1 YebY family protein -
IUJ51_RS08945 1713423..1714295 - 873 WP_000879296.1 copper homeostasis membrane protein CopD -
IUJ51_RS08950 1714299..1714673 - 375 WP_000168735.1 CopC domain-containing protein YobA -
IUJ51_RS08955 1714812..1715042 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IUJ51_RS08960 1715144..1715800 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
IUJ51_RS08965 1715824..1716486 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 / ipaH9.8 1684340..1757464 73124


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T181011 NZ_CP064376:c1712911-1712808 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT181011 NZ_CP064376:1712807-1713041 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGATAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References