Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 761211..761356 Replicon chromosome
Accession NZ_CP064352
Organism Klebsiella pneumoniae subsp. pneumoniae ATCC 43816

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 761247..761349 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 761211..761356 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT767_RS03515 756341..758401 + 2061 WP_004151449.1 oligopeptidase B -
IT767_RS03520 758405..759064 - 660 WP_038431281.1 exodeoxyribonuclease X -
IT767_RS03525 759143..759373 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IT767_RS03530 759486..759860 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IT767_RS03535 759864..760733 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
IT767_RS03540 760750..761088 + 339 WP_002911404.1 YebY family protein -
- 761211..761356 - 146 - - Antitoxin
- 761247..761349 + 103 - - Toxin
IT767_RS03545 761725..761868 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
IT767_RS03550 761973..762941 - 969 WP_014907334.1 VirK/YbjX family protein -
IT767_RS03555 763098..763751 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
IT767_RS03560 763748..763939 - 192 WP_002911395.1 YebW family protein -
IT767_RS03565 764037..764276 - 240 WP_002911393.1 YebV family protein -
IT767_RS03570 764392..765825 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180884 NZ_CP064352:761247-761349 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180884 NZ_CP064352:c761356-761211 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References