Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 1232897..1233693 | Replicon | chromosome |
| Accession | NZ_CP064334 | ||
| Organism | Xylella fastidiosa subsp. fastidiosa strain Bakersfield-8 | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | Q87CQ8 |
| Locus tag | IUD20_RS05455 | Protein ID | WP_004088112.1 |
| Coordinates | 1232897..1233508 (-) | Length | 204 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | B2I551 |
| Locus tag | IUD20_RS05460 | Protein ID | WP_004088114.1 |
| Coordinates | 1233505..1233693 (-) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IUD20_RS05410 | 1228352..1229239 | - | 888 | WP_012382597.1 | YdaU family protein | - |
| IUD20_RS05415 | 1229236..1230024 | - | 789 | WP_011097897.1 | Bro-N domain-containing protein | - |
| IUD20_RS05420 | 1230021..1230653 | - | 633 | WP_004088094.1 | Bro-N domain-containing protein | - |
| IUD20_RS05425 | 1230650..1230934 | - | 285 | WP_004088096.1 | hypothetical protein | - |
| IUD20_RS05430 | 1230931..1231179 | - | 249 | WP_011097898.1 | hypothetical protein | - |
| IUD20_RS05435 | 1231176..1231364 | - | 189 | WP_004088102.1 | hypothetical protein | - |
| IUD20_RS05440 | 1231392..1231583 | - | 192 | WP_004088104.1 | hypothetical protein | - |
| IUD20_RS05445 | 1231842..1232087 | - | 246 | WP_004088108.1 | hypothetical protein | - |
| IUD20_RS05450 | 1232172..1232846 | + | 675 | WP_012382600.1 | helix-turn-helix transcriptional regulator | - |
| IUD20_RS05455 | 1232897..1233508 | - | 612 | WP_004088112.1 | Fic/DOC family protein | Toxin |
| IUD20_RS05460 | 1233505..1233693 | - | 189 | WP_004088114.1 | antitoxin VbhA family protein | Antitoxin |
| IUD20_RS05465 | 1234085..1234621 | + | 537 | WP_012382601.1 | hypothetical protein | - |
| IUD20_RS05470 | 1234618..1235031 | + | 414 | WP_004088056.1 | DUF1566 domain-containing protein | - |
| IUD20_RS05475 | 1235028..1235429 | + | 402 | WP_004088054.1 | hypothetical protein | - |
| IUD20_RS05480 | 1235426..1235575 | + | 150 | WP_012382602.1 | hypothetical protein | - |
| IUD20_RS05485 | 1235661..1235939 | + | 279 | WP_004088050.1 | hypothetical protein | - |
| IUD20_RS05490 | 1235962..1236153 | + | 192 | WP_012382603.1 | hypothetical protein | - |
| IUD20_RS05495 | 1236174..1236518 | + | 345 | WP_004088346.1 | hypothetical protein | - |
| IUD20_RS05500 | 1236558..1237379 | + | 822 | WP_004088345.1 | DUF2303 family protein | - |
| IUD20_RS05505 | 1237395..1238321 | + | 927 | WP_004088344.1 | phage recombination protein Bet | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22832.60 Da Isoelectric Point: 5.1271
>T180854 WP_004088112.1 NZ_CP064334:c1233508-1232897 [Xylella fastidiosa subsp. fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
>T180854 NZ_CP085757:c526029-525544 [Enterobacter hormaechei]
GTGGGGCGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGCGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACATTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGTAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATACTTGCCCGTCTGGCTGTTGATGTCTCGTTACGCGGAAACGGGCTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATTGGGGTGCGGGCGATCATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCCGGCTTCCT
CAGTAG
GTGGGGCGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGCGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACATTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGTAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATACTTGCCCGTCTGGCTGTTGATGTCTCGTTACGCGGAAACGGGCTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATTGGGGTGCGGGCGATCATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCCGGCTTCCT
CAGTAG
Antitoxin
Download Length: 63 a.a. Molecular weight: 6837.77 Da Isoelectric Point: 4.9859
>AT180854 WP_004088114.1 NZ_CP064334:c1233693-1233505 [Xylella fastidiosa subsp. fastidiosa]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQIA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQIA
Download Length: 189 bp
>AT180854 NZ_CP085757:c526283-526017 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGTACAGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTTATCCTCGATCGACGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCGCAGTGGGGCGTGTAA
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGTACAGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTTATCCTCGATCGACGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCGCAGTGGGGCGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|