Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2454099..2454782 Replicon chromosome
Accession NZ_CP064325
Organism Xylella fastidiosa subsp. multiplex strain Red Oak

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IUD24_RS10820 Protein ID WP_004086858.1
Coordinates 2454099..2454527 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IUD24_RS10825 Protein ID WP_004086856.1
Coordinates 2454528..2454782 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUD24_RS10790 2450653..2451414 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
IUD24_RS10815 2452615..2454009 + 1395 WP_012338158.1 hypothetical protein -
IUD24_RS10820 2454099..2454527 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
IUD24_RS10825 2454528..2454782 - 255 WP_004086856.1 hypothetical protein Antitoxin
IUD24_RS10830 2454907..2455449 + 543 WP_012338159.1 hypothetical protein -
IUD24_RS10835 2455770..2456143 - 374 Protein_2108 DUF596 domain-containing protein -
IUD24_RS10840 2456155..2456487 - 333 WP_076613248.1 DUF769 domain-containing protein -
IUD24_RS10845 2456659..2457054 - 396 WP_193329301.1 DUF596 domain-containing protein -
IUD24_RS10850 2457061..2457414 - 354 Protein_2111 DUF769 domain-containing protein -
IUD24_RS10855 2457592..2457975 - 384 WP_004086848.1 DUF596 domain-containing protein -
IUD24_RS10860 2457980..2459017 - 1038 WP_012338161.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T180816 WP_004086858.1 NZ_CP064325:c2454527-2454099 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T180816 NZ_CP085743:c3102610-3102308 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
TTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCCGTGGGGGAAGGTATCAGTGAACTGAGGATCC
ACTTTGGCCCGGGCTACAGAGTCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT180816 WP_004086856.1 NZ_CP064325:c2454782-2454528 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT180816 NZ_CP085743:c3102301-3102014 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGGTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCTGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTAGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References