Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2010462..2010607 | Replicon | chromosome |
| Accession | NZ_CP064235 | ||
| Organism | Klebsiella pneumoniae strain JX-CR-hvKP-4 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2010498..2010600 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2010462..2010607 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IS499_RS09835 | 2005592..2007652 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| IS499_RS09840 | 2007656..2008315 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| IS499_RS09845 | 2008394..2008624 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| IS499_RS09850 | 2008737..2009111 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| IS499_RS09855 | 2009115..2009984 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| IS499_RS09860 | 2010001..2010339 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2010462..2010607 | - | 146 | - | - | Antitoxin |
| - | 2010498..2010600 | + | 103 | - | - | Toxin |
| IS499_RS09865 | 2010975..2011118 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| IS499_RS09870 | 2011223..2012191 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| IS499_RS09875 | 2012348..2013001 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| IS499_RS09880 | 2012998..2013189 | - | 192 | WP_002911395.1 | YebW family protein | - |
| IS499_RS09885 | 2013287..2013526 | - | 240 | WP_002911393.1 | YebV family protein | - |
| IS499_RS09890 | 2013642..2015075 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T180638 NZ_CP064235:2010498-2010600 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT180638 NZ_CP064235:c2010607-2010462 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
