Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2020931..2021076 | Replicon | chromosome |
| Accession | NZ_CP064232 | ||
| Organism | Klebsiella pneumoniae strain JX-CR-hvKP-5 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2020967..2021069 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2020931..2021076 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IS503_RS09575 | 2016061..2018121 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| IS503_RS09580 | 2018125..2018784 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| IS503_RS09585 | 2018863..2019093 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| IS503_RS09590 | 2019206..2019580 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| IS503_RS09595 | 2019584..2020453 | + | 870 | WP_014907333.1 | copper homeostasis membrane protein CopD | - |
| IS503_RS09600 | 2020470..2020808 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2020931..2021076 | - | 146 | - | - | Antitoxin |
| - | 2020967..2021069 | + | 103 | - | - | Toxin |
| IS503_RS09605 | 2021444..2021587 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| IS503_RS09610 | 2021692..2022660 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| IS503_RS09615 | 2022817..2023470 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| IS503_RS09620 | 2023467..2023658 | - | 192 | WP_002911395.1 | YebW family protein | - |
| IS503_RS09625 | 2023756..2023995 | - | 240 | WP_002911393.1 | YebV family protein | - |
| IS503_RS09630 | 2024111..2025544 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T180616 NZ_CP064232:2020967-2021069 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT180616 NZ_CP064232:c2021076-2020931 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
