Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3315206..3315351 Replicon chromosome
Accession NZ_CP064174
Organism Klebsiella pneumoniae strain 19110124

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3315213..3315315 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3315206..3315351 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU39_RS16315 3310738..3312171 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISU39_RS16320 3312287..3312526 + 240 WP_002911393.1 YebV family protein -
ISU39_RS16325 3312624..3312815 + 192 WP_002911395.1 YebW family protein -
ISU39_RS16330 3312812..3313465 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
ISU39_RS16335 3313622..3314590 + 969 WP_004151446.1 VirK/YbjX family protein -
ISU39_RS16340 3314695..3314838 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3315206..3315351 + 146 - - Antitoxin
- 3315213..3315315 - 103 - - Toxin
ISU39_RS16345 3315474..3315812 - 339 WP_016529031.1 YebY family protein -
ISU39_RS16350 3315829..3316698 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ISU39_RS16355 3316702..3317076 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ISU39_RS16360 3317189..3317419 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ISU39_RS16365 3317498..3318157 + 660 WP_032425085.1 exodeoxyribonuclease X -
ISU39_RS16370 3318161..3320221 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180411 NZ_CP064174:c3315315-3315213 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180411 NZ_CP064174:3315206-3315351 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References