Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1942308..1942453 Replicon chromosome
Accession NZ_CP064129
Organism Klebsiella pneumoniae strain M911-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1942315..1942417 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1942308..1942453 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD52_RS09680 1937839..1939272 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IOD52_RS09685 1939388..1939627 + 240 WP_002911393.1 YebV family protein -
IOD52_RS09690 1939725..1939916 + 192 WP_002911395.1 YebW family protein -
IOD52_RS09695 1939913..1940566 - 654 WP_023280291.1 protein-serine/threonine phosphatase -
IOD52_RS09700 1940723..1941691 + 969 WP_004151446.1 VirK/YbjX family protein -
IOD52_RS09705 1941796..1941939 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1942308..1942453 + 146 - - Antitoxin
- 1942315..1942417 - 103 - - Toxin
IOD52_RS09710 1942576..1942914 - 339 WP_002911404.1 YebY family protein -
IOD52_RS09715 1942931..1943800 - 870 WP_023280292.1 copper homeostasis membrane protein CopD -
IOD52_RS09720 1943804..1944178 - 375 WP_004151448.1 CopC domain-containing protein YobA -
IOD52_RS09725 1944291..1944521 + 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD52_RS09730 1944600..1945259 + 660 WP_002911407.1 exodeoxyribonuclease X -
IOD52_RS09735 1945263..1947323 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180351 NZ_CP064129:c1942417-1942315 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180351 NZ_CP064129:1942308-1942453 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References