Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2745322..2745416 Replicon chromosome
Accession NZ_CP064128
Organism Yersinia pestis strain M2086

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2745323..2745416 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2745322..2745416 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU65_RS12260 2740515..2742593 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU65_RS12265 2742593..2743753 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU65_RS12270 2744285..2744743 + 459 WP_002211098.1 hypothetical protein -
ISU65_RS12275 2744737..2745063 + 327 WP_002211097.1 DUF1493 family protein -
- 2745322..2745416 + 95 - - Antitoxin
- 2745323..2745416 - 94 - - Toxin
ISU65_RS12280 2745586..2745927 - 342 WP_002211095.1 YebY family protein -
ISU65_RS12285 2746024..2746908 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU65_RS12290 2746911..2747297 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU65_RS12295 2747694..2748203 - 510 WP_002211092.1 non-heme ferritin -
ISU65_RS12300 2748604..2748834 + 231 WP_002211091.1 DNA polymerase III subunit theta -
ISU65_RS12305 2748894..2749844 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - fliZ / fliA / fliD / fliS / fliT / fliE / fliF / fliG / fliH / fliI / fliJ / fliL / fliM / fliN / fliP / fliQ / fliR / flgL / flgK / flgJ / flgI / flgH / flgG / flgF / flgE / flgD / flgC / flgB / flgA / flgM / flgN / flhE / flhA / flhB 2639222..2748834 109612


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T180340 NZ_CP064128:c2745416-2745323 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180340 NZ_CP064128:2745322-2745416 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References