Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2485459..2485553 Replicon chromosome
Accession NZ_CP064126
Organism Yersinia pestis strain I-1252

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2485460..2485553 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2485459..2485553 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU63_RS11175 2480652..2482730 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU63_RS11180 2482730..2483890 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU63_RS11185 2484422..2484880 + 459 WP_002211098.1 hypothetical protein -
ISU63_RS11190 2484874..2485200 + 327 WP_002211097.1 DUF1493 family protein -
- 2485459..2485553 + 95 - - Antitoxin
- 2485460..2485553 - 94 - - Toxin
ISU63_RS11195 2485723..2486064 - 342 WP_002211095.1 YebY family protein -
ISU63_RS11200 2486161..2487045 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU63_RS11205 2487048..2487434 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU63_RS11210 2487831..2488340 - 510 WP_002211092.1 non-heme ferritin -
ISU63_RS11215 2488741..2488971 + 231 WP_002211091.1 DNA polymerase III subunit theta -
ISU63_RS11220 2489031..2489981 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T180315 NZ_CP064126:c2485553-2485460 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180315 NZ_CP064126:2485459-2485553 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References