Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2867753..2867847 Replicon chromosome
Accession NZ_CP064125
Organism Yersinia pestis strain M2085

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2867754..2867847 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2867753..2867847 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU62_RS12725 2862946..2865024 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU62_RS12730 2865024..2866184 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU62_RS12735 2866716..2867174 + 459 WP_002211098.1 hypothetical protein -
ISU62_RS12740 2867168..2867494 + 327 WP_002211097.1 DUF1493 family protein -
- 2867753..2867847 + 95 - - Antitoxin
- 2867754..2867847 - 94 - - Toxin
ISU62_RS12745 2868017..2868358 - 342 WP_002211095.1 YebY family protein -
ISU62_RS12750 2868455..2869339 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU62_RS12755 2869342..2869728 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU62_RS12760 2870152..2870661 - 510 WP_002211092.1 non-heme ferritin -
ISU62_RS12765 2871062..2871292 + 231 WP_002211091.1 DNA polymerase III subunit theta -
ISU62_RS12770 2871352..2872302 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T180301 NZ_CP064125:c2867847-2867754 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180301 NZ_CP064125:2867753-2867847 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References