Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2576738..2576832 Replicon chromosome
Accession NZ_CP064118
Organism Yersinia pestis strain C-783

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2576739..2576832 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2576738..2576832 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU55_RS11805 2571931..2574009 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU55_RS11810 2574009..2575169 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU55_RS11815 2575701..2576159 + 459 WP_002211098.1 hypothetical protein -
ISU55_RS11820 2576153..2576479 + 327 WP_002211097.1 DUF1493 family protein -
- 2576738..2576832 + 95 - - Antitoxin
- 2576739..2576832 - 94 - - Toxin
ISU55_RS11825 2577002..2577343 - 342 WP_002211095.1 YebY family protein -
ISU55_RS11830 2577440..2578324 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU55_RS11835 2578327..2578713 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU55_RS11840 2579119..2579628 - 510 WP_002211092.1 non-heme ferritin -
ISU55_RS11845 2580029..2580259 + 231 WP_140270001.1 DNA polymerase III subunit theta -
ISU55_RS11850 2580319..2581269 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - fliZ / fliA / fliD / fliS / fliT / fliE / fliF / fliG / fliH / fliI / fliJ / fliL / fliM / fliN / fliP / fliQ / fliR / flgL / flgK / flgJ / flgI / flgH / flgG / flgF / flgE / flgD / flgC / flgB / flgA / flgM / flgN / flhE / flhA / flhB 2458561..2580259 121698


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T180210 NZ_CP064118:c2576832-2576739 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180210 NZ_CP064118:2576738-2576832 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References