Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2178872..2179431 Replicon chromosome
Accession NZ_CP064037
Organism Vibrio parahaemolyticus strain XMM117

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H9J99_RS10125 Protein ID WP_053312146.1
Coordinates 2179153..2179431 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9J99_RS10120 Protein ID WP_053312147.1
Coordinates 2178872..2179156 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9J99_RS10090 (H9J99_10020) 2174216..2174968 - 753 WP_248339883.1 IS21-like element helper ATPase IstB -
H9J99_RS10095 (H9J99_10025) 2174984..2176525 - 1542 WP_248339881.1 IS21 family transposase -
H9J99_RS10100 (H9J99_10030) 2176753..2177160 - 408 WP_282575046.1 NAD(P)H-dependent oxidoreductase -
H9J99_RS10105 2177149..2177235 - 87 Protein_1953 DUF3265 domain-containing protein -
H9J99_RS10110 (H9J99_10035) 2177253..2177729 - 477 WP_029836910.1 GNAT family N-acetyltransferase -
H9J99_RS10115 (H9J99_10040) 2177849..2178670 - 822 WP_020840798.1 DUF2002 family protein -
H9J99_RS10120 (H9J99_10045) 2178872..2179156 + 285 WP_053312147.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H9J99_RS10125 (H9J99_10050) 2179153..2179431 + 279 WP_053312146.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
H9J99_RS10130 (H9J99_10055) 2179569..2180015 - 447 WP_031817701.1 GNAT family N-acetyltransferase -
H9J99_RS10135 (H9J99_10060) 2180630..2180722 - 93 WP_222133812.1 DUF3265 domain-containing protein -
H9J99_RS10140 (H9J99_10065) 2180737..2181186 - 450 WP_176296809.1 hypothetical protein -
H9J99_RS10145 (H9J99_10070) 2181189..2181533 - 345 WP_176296810.1 hypothetical protein -
H9J99_RS10150 (H9J99_10075) 2181660..2182094 - 435 WP_100088283.1 GNAT family N-acetyltransferase -
H9J99_RS10155 (H9J99_10080) 2182255..2182809 - 555 WP_053319305.1 YkgJ family cysteine cluster protein -
H9J99_RS10160 (H9J99_10085) 2182837..2182926 - 90 WP_071881309.1 DUF3265 domain-containing protein -
H9J99_RS10165 (H9J99_10090) 2183449..2183541 - 93 WP_079751132.1 DUF3265 domain-containing protein -
H9J99_RS10170 (H9J99_10095) 2183569..2184252 - 684 WP_069529237.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2135070..2247242 112172
- inside Integron - - 2176753..2212601 35848


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10880.55 Da        Isoelectric Point: 4.3324

>T179974 WP_053312146.1 NZ_CP064037:2179153-2179431 [Vibrio parahaemolyticus]
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIETKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSVIRIM
RVLHQKQKFPTD

Download         Length: 279 bp

>T179974 NZ_CP084921:1791798-1791980 [Acinetobacter pittii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10913.19 Da        Isoelectric Point: 8.0515

>AT179974 WP_053312147.1 NZ_CP064037:2178872-2179156 [Vibrio parahaemolyticus]
MDTRIQFRVDDEVKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDNWLTEQVNLAFEKFDSGKASFVDHDSAKAR
MAERKAKIRNRGQQ

Download         Length: 285 bp

>AT179974 NZ_CP084921:1792073-1792477 [Acinetobacter pittii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References