Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3747733..3748283 Replicon chromosome
Accession NZ_CP064030
Organism Dyella caseinilytica strain DHOB09

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ISN74_RS16610 Protein ID WP_188800273.1
Coordinates 3747978..3748283 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ISN74_RS16605 Protein ID WP_188800272.1
Coordinates 3747733..3747990 (+) Length 86 a.a.

Genomic Context

ISN74_RS16585ISN74_RS16590ISN74_RS16595ISN74_RS16600ISN74_RS16605ISN74_RS16610ISN74_RS16615ISN74_RS16620ISN74_RS16625
Location: 3743361..3744296 (936 bp)
Type: Others
Protein ID: WP_188800268.1
Location: 3744327..3744680 (354 bp)
Type: Others
Protein ID: WP_203546772.1
Location: 3744709..3745380 (672 bp)
Type: Others
Protein ID: WP_188800270.1
Location: 3745493..3747631 (2139 bp)
Type: Others
Protein ID: WP_188800271.1
Location: 3747733..3747990 (258 bp)
Type: Antitoxin
Protein ID: WP_188800272.1
Location: 3747978..3748283 (306 bp)
Type: Toxin
Protein ID: WP_188800273.1
Location: 3748362..3749963 (1602 bp)
Type: Others
Protein ID: WP_188800274.1
Location: 3750053..3750997 (945 bp)
Type: Others
Protein ID: WP_188800275.1
Location: 3750963..3751436 (474 bp)
Type: Others
Protein ID: WP_188800276.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ISN74_RS165853743361..3744296+936WP_188800268.1carbohydrate kinase family protein-
ISN74_RS165903744327..3744680+354WP_203546772.1DUF1304 domain-containing protein-
ISN74_RS165953744709..3745380+672WP_188800270.1aminopeptidase P family protein-
ISN74_RS166003745493..3747631+2139WP_188800271.1elongation factor G-
ISN74_RS166053747733..3747990+258WP_188800272.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
ISN74_RS166103747978..3748283+306WP_188800273.1type II toxin-antitoxin system RelE/ParE family toxinToxin
ISN74_RS166153748362..3749963+1602WP_188800274.1peptide chain release factor 3-
ISN74_RS166203750053..3750997+945WP_188800275.1CPBP family intramembrane metalloprotease-
ISN74_RS166253750963..3751436-474WP_188800276.1DUF4442 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11822.51 Da        Isoelectric Point: 7.2776

>T179966 WP_188800273.1 NZ_CP064030:3747978-3748283 [Dyella caseinilytica]
MAEIIWTEPALSELDEIADYIALDNPQAARDLVHRVFQHVEQLAEHPESGSRPSELKKSRYRQIVEPPCRIFYRFDGKAL
IILYVMRSERSLRRSRLADRG

Download         Length: 306 bp

>T179966 NZ_CP084914:2531759-2532160 [Leptospira borgpetersenii]
ATGACTCAATACTTATTAGATACGAATATTTGCATTTATATAATAAACCAAAAGCCGAGGTCTGTTTATAAAAAATTTAA
AAAGATCAAGTTAGAAAACATATTTATTTCATCAATTACGGAATTTGAATTAAAGTATGGCGTTCAAAAAAGTCTTCATT
TCGAAAGGGACTTAAAAATTTTAGAAGAGTTTTTAAGTTATTTGAATATTCTTTCATTTGTTAGTGAGGACGCGAATAAA
GCTGCAAAAATTCGAGTAGAATTAGACAAAGTGGGGAAACCAATCGGTCCTTTCGATCTTTTAATAGCTTCTCAAGCGTT
ATCGAATAAACTTACTCTCGTAACGAACAATGAAAAAGAGTTTACTCGGATCAAAGATATTAAAATTGCAAACTGGCTTT
AA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9983.45 Da        Isoelectric Point: 7.2062

>AT179966 WP_188800272.1 NZ_CP064030:3747733-3747990 [Dyella caseinilytica]
MRTELVTTLKRQATELLAELERDREPILITQHGLPTAYLVDVDSFEAMQQRVRLLEGIARGERAVDEERTLTHDQARTRL
KRWLK

Download         Length: 258 bp

>AT179966 NZ_CP084914:2531532-2531762 [Leptospira borgpetersenii]
ATGAATAAAGCTAAAATTTTTAAAAATGGGGATAGTCAAGCAATTCGTTTACCGAAAGACTATCGTTTCAAAGGCAAAGA
AGTCTATATACGAAGGGATGGAGATAATGTTATCTTAACGCCAATAAACGATGCGGTTGATCGTTTTTGGAATACGGTTA
ATAGCTTTTCTGACGATCTTATACTTGATCGAAACCAACCAAACGAGTATGGCAAACGAAATAAAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References