Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3747733..3748283 Replicon chromosome
Accession NZ_CP064030
Organism Dyella caseinilytica strain DHOB09

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ISN74_RS16610 Protein ID WP_188800273.1
Coordinates 3747978..3748283 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ISN74_RS16605 Protein ID WP_188800272.1
Coordinates 3747733..3747990 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN74_RS16585 3743361..3744296 + 936 WP_188800268.1 carbohydrate kinase family protein -
ISN74_RS16590 3744327..3744680 + 354 WP_203546772.1 DUF1304 domain-containing protein -
ISN74_RS16595 3744709..3745380 + 672 WP_188800270.1 aminopeptidase P family protein -
ISN74_RS16600 3745493..3747631 + 2139 WP_188800271.1 elongation factor G -
ISN74_RS16605 3747733..3747990 + 258 WP_188800272.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ISN74_RS16610 3747978..3748283 + 306 WP_188800273.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ISN74_RS16615 3748362..3749963 + 1602 WP_188800274.1 peptide chain release factor 3 -
ISN74_RS16620 3750053..3750997 + 945 WP_188800275.1 CPBP family intramembrane metalloprotease -
ISN74_RS16625 3750963..3751436 - 474 WP_188800276.1 DUF4442 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11822.51 Da        Isoelectric Point: 7.2776

>T179966 WP_188800273.1 NZ_CP064030:3747978-3748283 [Dyella caseinilytica]
MAEIIWTEPALSELDEIADYIALDNPQAARDLVHRVFQHVEQLAEHPESGSRPSELKKSRYRQIVEPPCRIFYRFDGKAL
IILYVMRSERSLRRSRLADRG

Download         Length: 306 bp

>T179966 NZ_CP084914:2531759-2532160 [Leptospira borgpetersenii]
ATGACTCAATACTTATTAGATACGAATATTTGCATTTATATAATAAACCAAAAGCCGAGGTCTGTTTATAAAAAATTTAA
AAAGATCAAGTTAGAAAACATATTTATTTCATCAATTACGGAATTTGAATTAAAGTATGGCGTTCAAAAAAGTCTTCATT
TCGAAAGGGACTTAAAAATTTTAGAAGAGTTTTTAAGTTATTTGAATATTCTTTCATTTGTTAGTGAGGACGCGAATAAA
GCTGCAAAAATTCGAGTAGAATTAGACAAAGTGGGGAAACCAATCGGTCCTTTCGATCTTTTAATAGCTTCTCAAGCGTT
ATCGAATAAACTTACTCTCGTAACGAACAATGAAAAAGAGTTTACTCGGATCAAAGATATTAAAATTGCAAACTGGCTTT
AA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9983.45 Da        Isoelectric Point: 7.2062

>AT179966 WP_188800272.1 NZ_CP064030:3747733-3747990 [Dyella caseinilytica]
MRTELVTTLKRQATELLAELERDREPILITQHGLPTAYLVDVDSFEAMQQRVRLLEGIARGERAVDEERTLTHDQARTRL
KRWLK

Download         Length: 258 bp

>AT179966 NZ_CP084914:2531532-2531762 [Leptospira borgpetersenii]
ATGAATAAAGCTAAAATTTTTAAAAATGGGGATAGTCAAGCAATTCGTTTACCGAAAGACTATCGTTTCAAAGGCAAAGA
AGTCTATATACGAAGGGATGGAGATAATGTTATCTTAACGCCAATAAACGATGCGGTTGATCGTTTTTGGAATACGGTTA
ATAGCTTTTCTGACGATCTTATACTTGATCGAAACCAACCAAACGAGTATGGCAAACGAAATAAAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References