Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4103605..4104053 Replicon chromosome
Accession NZ_CP064005
Organism Xanthomonas translucens pv. translucens strain XtKm7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ISN30_RS17640 Protein ID WP_206709583.1
Coordinates 4103605..4103757 (+) Length 51 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ISN30_RS17645 Protein ID WP_009580422.1
Coordinates 4103760..4104053 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISN30_RS17620 4099149..4100762 + 1614 WP_206709582.1 PAS domain-containing sensor histidine kinase -
ISN30_RS17625 4100837..4102225 + 1389 WP_060748005.1 sigma-54 dependent transcriptional regulator -
ISN30_RS17630 4102390..4102553 + 164 Protein_3464 type II toxin-antitoxin system RelE/ParE family toxin -
ISN30_RS17635 4102644..4103611 + 968 Protein_3465 IS1595 family transposase -
ISN30_RS17640 4103605..4103757 + 153 WP_206709583.1 addiction module killer protein Toxin
ISN30_RS17645 4103760..4104053 + 294 WP_009580422.1 putative addiction module antidote protein Antitoxin
ISN30_RS17650 4104081..4105817 - 1737 WP_206709584.1 type IV-A pilus assembly ATPase PilB -
ISN30_RS17655 4105933..4106310 + 378 WP_080603077.1 hypothetical protein -
ISN30_RS17660 4106556..4106993 - 438 WP_038232341.1 pilin -
ISN30_RS17665 4107378..4108637 + 1260 WP_064522057.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-48)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5698.55 Da        Isoelectric Point: 9.8064

>T179963 WP_206709583.1 NZ_CP064005:4103605-4103757 [Xanthomonas translucens pv. translucens]
VLVRIHHGPGYRVYFQRRGDTIIVLLCGGDKSTQAKDIKTAKRLADEWSE

Download         Length: 153 bp

>T179963 NZ_CP084910:402305-402601 [Asticcacaulis sp. AND118]
ATGACAGATACGCTGTTCGAATGGGATGACGTCAAGGCGCTGAGCAATCTCCGCAAACACGGCGTCGACTTCGATACGGC
GACACTGGTCTTTTACGACCCTTTCGCGGTTACGGAAATGGATCGTATTGAGGGCGGCGAGCAGCGTTGGCAGACACTGG
GCCGGGTCAACGATACGCTTCTGCTTCTGGTGGCCCATACCGTTTGGGATGACGACGACACAGAAATTATCCGCATCATT
TCCGCTCGACAGGCTGTACCCAAGGAAAGGCGAAAATATGAGCAGCAAAATCGTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10376.69 Da        Isoelectric Point: 4.9890

>AT179963 WP_009580422.1 NZ_CP064005:4103760-4104053 [Xanthomonas translucens pv. translucens]
MTENLTTYDPAEDLNSDQAIADFMAGAFATNDTGFIAHALGIVARAKGMTQIARQTGLSREQLYRSFSEDGNPTLRTTLA
VMKALGIELTAKAAVTH

Download         Length: 294 bp

>AT179963 NZ_CP084910:402582-402899 [Asticcacaulis sp. AND118]
ATGAGCAGCAAAATCGTTAGACGTATCTTCGACCCCGCTAATCCGCCGGTTCTGACCGAGGCGCAGAAGAGGCAACTCGA
AGCCTTGGCCGCACGTCCGGACAGTGAGATCGACGTCAGCGACATTCCGCCGCTGACCGATGGTTTCTGGGAAAACGCCC
TGCGCAATCCGTTTATGCGACCTGTCAAACAGCAGGCGACGGTACGTCTTGATGCCGATGTGCTCGACTGGCTCAAATCG
TCCGGCAAGGGCTATCAGACGCGACTCAACGCGATCCTGCGCAAGGAAATGCTGGCCGATCTCAAACGGCGCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References